Do cross-reactive antibodies cause neuropathology in COVID-19?

Do cross-reactive antibodies cause neuropathology in COVID-19?
复制标题

DOI:
10.1038/s41577-020-00458-y
复制
发表时间:
2020-11
期刊:
Nature reviews. Immunology
影响因子:
--
通讯作者:
Prüss H
Prüss H
中科院分区:
其他
文献类型:
--
作者:
Kreye J;Reincke SM;Prüss H

文献摘要

参考文献

被引文献

相似文献

神经系统症状见于 COVID-19 患者,并且在 SARS-CoV-2 清除后可能持续存在或重新出现。最近的研究结果表明,SARS-CoV-2 抗体可以与哺乳动物蛋白发生交叉反应。我们重点关注神经系统症状,讨论这些交叉反应抗体是否可能导致 COVID-19 疾病病理学以及清除初始病毒感染的患者症状持续存在。在 COVID-19 患者中越来越多地观察到神经系统症状;这篇评论文章考虑了交叉反应抗体是否可能导致与 SARS-CoV-2 感染相关的病理学。
Neurological symptoms are seen in patients with COVID-19 and can persist or re-emerge after clearance of SARS-CoV-2. Recent findings suggest that antibodies to SARS-CoV-2 can cross-react with mammalian proteins. Focusing on neurological symptoms, we discuss whether these cross-reactive antibodies could contribute to COVID-19 disease pathology and to the persistence of symptoms in patients who have cleared the initial viral infection. Neurological symptoms are increasingly being observed in patients with COVID-19; this Comment article considers whether cross-reactive antibodies might contribute to the pathology associated with SARS-CoV-2 infection.
DOI: 10.1002/ana.23689
发表时间: 2012-12
影响因子: 11.2
作者:
Pruess, Harald;Finke, Carsten;Hoeltje, Markus;Hofmann, Joerg;Klingbeil, Christine;Probst, Christian;Borowski, Kathrin;Ahnert-Hilger, Gudrun;Harms, Lutz;Schwab, Jan M.;Ploner, Christoph J.;Komorowski, Lars;Stoecker, Winfried;Dalmau, Josep;Wandinger, Klaus-Peter
通讯作者: Wandinger, Klaus-Peter
DOI: 10.1016/s1474-4422(18)30244-8
发表时间: 2018-09
期刊: The Lancet. Neurology
影响因子: --
作者:
Armangue T;Spatola M;Vlagea A;Mattozzi S;Cárceles-Cordon M;Martinez-Heras E;Llufriu S;Muchart J;Erro ME;Abraira L;Moris G;Monros-Giménez L;Corral-Corral Í;Montejo C;Toledo M;Bataller L;Secondi G;Ariño H;Martínez-Hernández E;Juan M;Marcos MA;Alsina L;Saiz A;Rosenfeld MR;Graus F;Dalmau J;Spanish Herpes Simplex Encephalitis Study Group
通讯作者: Spanish Herpes Simplex Encephalitis Study Group
DOI: 10.1016/j.cell.2020.06.044
发表时间: 2020-08-20
期刊: CELL
影响因子: 64.5
作者:
Kreer, Christoph;Zehner, Matthias;Klein, Florian
通讯作者: Klein, Florian
DOI: 10.1056/nejmoa2021436
发表时间: 2021-02-25
影响因子: 158.5
作者:
Horby, Peter;Lim, Wei Shen;Landray, Martin J.
通讯作者: Landray, Martin J.
DOI: 10.1016/j.bbi.2020.12.022
发表时间: 2021-03
期刊: Brain, behavior, and immunity
影响因子: --
作者:
Franke C;Ferse C;Kreye J;Reincke SM;Sanchez-Sendin E;Rocco A;Steinbrenner M;Angermair S;Treskatsch S;Zickler D;Eckardt KU;Dersch R;Hosp J;Audebert HJ;Endres M;Ploner JC;Prüß H
通讯作者: Prüß H