Procedural memory stimulation in Alzheimer's disease: impact of a training programme
Procedural memory stimulation in Alzheimer's disease: impact of a training programme
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阿尔茨海默病的程序性记忆刺激：训练计划的影响
DOI：
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发表时间：
1997
影响因子：
3.5
通讯作者：
M. Trabucchi
中科院分区：
文献类型：
--
作者：
O. Zanetti;G. Binetti;E. Magni;L. Rozzini;A. Bianchetti;M. Trabucchi
该研究评估了程序性记忆刺激程序在轻度和轻度-中度阿尔茨海默病（AD）中的疗效。选择了20种基本的和工具性的日常生活活动，并分为两组，难度相当。10名正常老年受试者（年龄68.0±4.8岁; MMSE评分：28.7±0.9;教育程度：7.6±3.5年）被要求完成两组日常活动，并记录完成每组任务所需的时间并用作参考。10例无严重行为障碍的轻度和轻度-中度AD患者（年龄77.2±5.3岁; MMSE评分：19.8±3.5;教育：7.3±4.7年）构成实验组。在基线和3周训练（1小时/天，5天/周）后，对患者的所有20项日常活动进行评价，并记录所用时间。5名患者在3周内接受了20项日常活动中一半的训练，其他5名患者接受了其余活动的训练。采用这一程序是为了分别检测“经过培训”和“未经培训”的活动的改善情况，以便更好地控制干预措施的效果。通过培训前后执行任务所用时间的变化，直接测量培训对功能影响的评估。经过3周的训练后，观察到训练活动的显著改善，从3.6到1.9个标准差，低于正常老年对照组的表现（P<0.05）。AD患者在未经训练的活动中也有所改善，比对照组的表现低3.5至2.7个标准差（P<0.05）。通过开发程序性记忆策略来恢复日常生活活动可能对轻度和轻中度AD患者有效。
The study evaluates the efficacy of a procedural memory stimulation programme in mild and mild‐moderate Alzheimer's disease (AD). Twenty basic and instrumental activities of daily living have been selected, and divided into two groups, comparable for difficulty. Ten normal elderly subjects (age 68.0±4.8 years; MMSE score: 28.7±0.9; education: 7.6±3.5 years) were asked to perform the two groups of daily activities and the time required to perform the tasks of each group was recorded and used as a reference. Ten mild and mild‐moderate AD patients (age 77.2±5.3 years; MMSE score: 19.8±3.5; education: 7.3±4.7 years) without major behavioural disturbances constituted the experimental group. Patients were evaluated in all 20 daily activities and the time employed was recorded at baseline and after a 3‐week training (1 h/d, 5 d/week) period. Five patients were trained during the 3 weeks on half of the 20 daily activities and the other five patients were trained on the remainder. This procedure was adopted in order to detect separately the improvement in “trained” and “not trained” activities, allowing to control better the effects of the intervention. The assessment of the functional impact of the training was directly measured, through the variation of time employed to perform tasks before and after training. After 3 weeks of training a significant improvement was observed for the trained activities, from 3.6 to 1.9 standard deviations below the performance of the normal elderly controls (P<0.05). AD patients improved also in not‐trained activities from 3.5 to 2.7 standard deviations below the controls’performance (P<0.05). The rehabilitation of activities of daily living through developing procedural memory strategies may be effective in mild and mild‐moderate AD patients.
DOI：
10.1037//0278-7393.10.1.164
发表时间：
1984
期刊：
Journal of experimental psychology. Learning, memory, and cognition
影响因子：
--
作者：
P. Graf;L. Squire;G. Mandler
通讯作者：
P. Graf;L. Squire;G. Mandler
正常和痴呆老年人群的记忆训练：E-I-E-I-O 模型。
影响因子：
1.8
作者：
Camp,CJ;Foss,JW;Stevens,AB;Reichard,CC;McKitrick,LA;O'Hanlon,AM
通讯作者：
O'Hanlon,AM
基于家庭的策略对阿尔茨海默病的不同影响。
DOI：
10.1093/geront/29.2.150
发表时间：
1989
期刊：
The Gerontologist
影响因子：
--
作者：
Quayhagen,MP;Quayhagen,M
通讯作者：
Quayhagen,M