Can O6-alkylguanine-DNA alkyltransferase depletion enhance alkylator activity in the clinic?
Can O6-alkylguanine-DNA alkyltransferase depletion enhance alkylator activity in the clinic?
复制标题
O6-烷基鸟嘌呤-DNA 烷基转移酶消耗能否增强临床中烷化剂的活性?
DOI:
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复制
发表时间:
2000
影响因子:
11.5
通讯作者:
H. Friedman
中科院分区:
文献类型:
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作者:
H. Friedman
Resistance to chemotherapy remains an essential reason for the failure to cure patients with a diverse spectrum of malignancies. Malignant tumors, particularly those arising in adults, demonstrate a broad range of de novo or acquired mechanisms of resistance to virtually all chemotherapeutic agents
DOI:
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发表时间:
2000-08
期刊:
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子:
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作者:
R. Schilsky;M. Dolan;D. Bertucci;R. Ewesuedo;N. Vogelzang;S. Mani;L. R. Wilson;M. Ratain
通讯作者:
R. Schilsky;M. Dolan;D. Bertucci;R. Ewesuedo;N. Vogelzang;S. Mani;L. R. Wilson;M. Ratain
影响因子:
45.3
作者:
Friedman, HS;Kokkinakis, DM;Schold, SC
通讯作者:
Schold, SC
影响因子:
7.4
作者:
Rettori MM;de Carvalho AC;Longo AL;de Oliveira CZ;Kowalski LP;Carvalho AL;Vettore AL
通讯作者:
Vettore AL