Development and regeneration of the crushing dentition in skates (Rajidae).
Development and regeneration of the crushing dentition in skates (Rajidae).
复制标题
鳐鱼（Rajidae）破碎齿列的发育和再生。
DOI：
10.1016/j.ydbio.2020.07.014
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发表时间：
2020
影响因子：
2.7
通讯作者：
Rasch LJ
中科院分区：
文献类型：
--
作者：
Rasch LJ
鲨鱼和鳐鱼（软骨鱼类）具有不断再生牙齿的非凡能力。多齿动物系统被认为是颚口动物牙列的祖先条件。尽管鲨鱼和鳐鱼具有共同的再生能力，但它们的牙齿形态却表现出巨大的种间差异。鳐鱼（batoidea）的牙齿通常由扁平牙齿组成，而鲨鱼的牙齿是尖的、多尖牙的单位。尽管最近的研究已经解决了鲨鱼牙列的分子发育问题，但人们对鳐鱼的分子发育知之甚少。此外，软骨鱼类谱系中的牙齿多样性是如何实现的仍然未知。在这里，我们研究了两种鳐鱼的牙齿发育和再生：刺背鳐鱼（Raja clavata）和小鳐鱼（Leucoraja erinacea）。使用原位杂交和免疫组织化学，我们检查了鳐鱼牙列早期发育过程中核心颌口牙齿基因组的表达，并将其与鲨鱼的发育进行比较。软骨鱼类的牙齿发育高度保守，sox2可能在牙齿的形成和再生中发挥重要作用。牙釉质结样信号中心表达的保守基因的改变可以解释软骨鱼牙齿的形态多样性，从而使鲨鱼和鳐鱼能够占据不同的饮食和生态位。
Sharks and rays (elasmobranchs) have the remarkable capacity to continuously regenerate their teeth. The polyphyodont system is considered the ancestral condition of the gnathostome dentition. Despite this shared regenerative ability, sharks and rays exhibit dramatic interspecific variation in their tooth morphology. Ray (batoidea) teeth typically constitute crushing pads of flattened teeth, whereas shark teeth are pointed, multi-cuspid units. Although recent research has addressed the molecular development of the shark dentition, little is known about that of the ray. Furthermore, how dental diversity within the elasmobranch lineage is achieved remains unknown. Here, we examine dental development and regeneration in two Batoid species: the thornback skate (Raja clavata) and the little skate (Leucoraja erinacea). Usingin situhybridization and immunohistochemistry, we examine the expression of a core gnathostome dental gene set during early development of the skate dentition and compare it to development in the shark. Elasmobranch tooth development is highly conserved, withsox2likely playing an important role in the initiation and regeneration of teeth. Alterations to conserved genes expressed in an enamel knot-like signalling centre may explain the morphological diversity of elasmobranch teeth, thereby enabling sharks and rays to occupy diverse dietary and ecological niches.
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影响因子：
2.7
作者：
Fraser, Gareth J.;Bloomquist, Ryan F.;Streelman, J. Todd
通讯作者：
Streelman, J. Todd
DOI：
10.1002/ar.20719
发表时间：
2008-09-01
影响因子：
2
作者：
Maxwell, Erin E.;Froebisch, Nadia B.;Heppleston, Audrey C.
通讯作者：
Heppleston, Audrey C.
影响因子：
3.7
作者：
KURKI, P;VANDERLAAN, M;TAN, EM
通讯作者：
TAN, EM
影响因子：
2.7
作者：
Mitsiadis, Thimios A.;Caton, Javier;Bluteau, Gilles
通讯作者：
Bluteau, Gilles
影响因子：
2.4
作者：
Freitas, R;Cohn, MJ
通讯作者：
Cohn, MJ