Gold nanorods and graphene oxide enhanced BSA-AgInS2 quantum dot-based photoelectrochemical sensors for detection of dopamine
Gold nanorods and graphene oxide enhanced BSA-AgInS2 quantum dot-based photoelectrochemical sensors for detection of dopamine
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金纳米棒和氧化石墨烯增强的 BSA-AgInS2 量子点光电化学传感器用于检测多巴胺
DOI：
10.1016/j.electacta.2018.11.121
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发表时间：
2019-02
影响因子：
6.6
通讯作者：
Yue Zhao
中科院分区：
文献类型：
--
作者：
Li Yunxiao;Li Zhengping;Ye Weixiang;Zhao Shuang;Yang Qiaochun;Ma Song;Xiao Gang;Liu Guohua;Wang Yong;Yue Zhao
基于量子点（QD）的光电化学（PEC）传感器由于其自身的优点而受到广泛的关注，但大多数量子点中重金属离子的存在限制了其在生化检测中的实际应用。在此，我们提出了一种基于牛血清白蛋白包被的AgInS2QDs （BSA-AgInS2）的低毒性PEC生物传感器，用于多巴胺（DA）的敏感检测。在本研究中，首先对制作和测量条件进行了优化。此外，还引入了不同的纳米材料作为杂化纳米复合材料来增强传感性能。实验结果表明，金纳米棒（aunr）改善了bsa - agins2qd型PEC传感器的光电性能，氧化石墨烯（GO）增强了bsa - agins2qd型PEC传感器的DA催化性能。在氧化石墨烯（0.17 mg/mL）和AuNRs（66.75 μg/mL）的最佳浓度下，基于BSA-AgInS2/AuNRs/GO的PEC传感器的灵敏度和检出限（LOD）在0.3 ~ 10 μM的线性范围内分别达到4.5 nA/μM和66.8 nM。此外，我们设计的PEC传感器对DA的选择性高于抗坏血酸（AA）和尿酸（UA）的干扰物质。从而证明了通过分别提高光电性能和催化性能来提高PEC传感器传感性能的通用策略。
Quantum dot (QD)-based photoelectrochemical (PEC) sensors have attracted considerable attention owing to their advantages, while the heavy metal ions existed in most investigated QDs limit their practical applications in biochemical detection. Herein, we present a PEC biosensor based on bovine serum albumin-coated AgInS2QDs (BSA-AgInS2) with low toxicity for the sensitive detection of dopamine (DA). In this study, the fabrication and measurement conditions were optimized first. Furthermore, different nanomaterials were introduced as hybrid nanocomposites to enhance the sensing properties. The experimental results revealed that gold nanorods (AuNRs) improved the photoelectric properties, and graphene oxide (GO) enhanced the catalytic properties on DA of BSA-AgInS2QD-based PEC sensors. Due to the enhancement effects of both GO and AuNRs, the sensitivity and limit of detection (LOD) of BSA-AgInS2/AuNRs/GO-based PEC sensors reached 4.5 nA/μM and 66.8 nM, respectively, in the linear range of 0.3–10 μM when optimal concentrations of GO (0.17 mg/mL) and AuNRs (66.75 μg/mL) were used. Moreover, our designed PEC sensors showed high selectivity for DA over the interfering substances of ascorbic acid (AA) and uric acid (UA). Thus, a universal strategy to enhance the sensing properties of PEC sensors by the improvement of photoelectric and catalytic properties separately was proven.
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影响因子：
3.7
作者：
Ibrahim, Izwaharyanie;Lim, Hong Ngee;Pandikumar, Alagarsamy
通讯作者：
Pandikumar, Alagarsamy
影响因子：
6.7
作者：
Weiwei Zhao;Xiaodong Yu;Jingjuan Xu;Hongyuan Chen
通讯作者：
Weiwei Zhao;Xiaodong Yu;Jingjuan Xu;Hongyuan Chen
影响因子：
8.4
作者：
Qi Kang;W. Xuxiang;Xiaolong Ma;Lingqian Kong;Ping Zhang;Dazhong Shen
通讯作者：
Qi Kang;W. Xuxiang;Xiaolong Ma;Lingqian Kong;Ping Zhang;Dazhong Shen
影响因子：
6.4
作者：
Pyng Yu;X. Wen;Yon‐Rui Toh;Yu-Chieh Lee;Kuo-Yen Huang;Shujuan Huang;S. Shrestha;G. Conibeer;Jau Tang
通讯作者：
Pyng Yu;X. Wen;Yon‐Rui Toh;Yu-Chieh Lee;Kuo-Yen Huang;Shujuan Huang;S. Shrestha;G. Conibeer;Jau Tang
影响因子：
6.1
作者：
E. Aazam
通讯作者：
E. Aazam