Identifying physiological measures of lifetime welfare status in pigs: exploring the usefulness of haptoglobin, C- reactive protein and hair cortisol sampled at the time of slaughter.
Identifying physiological measures of lifetime welfare status in pigs: exploring the usefulness of haptoglobin, C- reactive protein and hair cortisol sampled at the time of slaughter.
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DOI：
10.1186/s13620-018-0118-0
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发表时间：
2018
影响因子：
2.9
通讯作者：
O'Connell NE
中科院分区：
文献类型：
--
作者：
Carroll GA;Boyle LA;Hanlon A;Palmer MA;Collins L;Griffin K;Armstrong D;O'Connell NE
在饲养过程中动物福利状况的生理指标可以构成屠宰场动物健康和福利评估工具的一部分。本研究共使用了66头猪，其目的是评估在屠宰时或接近屠宰时测量的血清结合珠蛋白（Hp）和C反应蛋白（CRP）浓度（在51头猪中评估）以及毛发皮质醇浓度（在65头猪中评估）如何反映动物一生中记录的福利相关指标。这些指标在7至21周龄之间的时间间隔进行记录，包括对尾部和皮肤病变的水平进行评分，记录是否存在某些健康问题，并进行定性行为评估（QBA）。在其一生中记录有尾部病变的猪比没有尾部病变的猪有更高的毛发皮质醇水平（尾部病变：47.87 ± 3.34 pg/mg，无尾部病变：42.20 ± 3.29 pg/mg，P = 0.023），并且记录为具有中度或重度尾部病变的猪比无或轻度尾部病变的猪具有更高的Hp水平（中度/重度：1.711 mg/ml ± 0.74，无/轻度：0.731 mg/ml ±0.10，P = 0.010）。在其一生中记录为跛行的猪往往具有比非跛行猪更高的毛发皮质醇水平（跛行：52.72 pg/mg ± 3.83，非跛行：43.07 pg/mg ± 2.69，P = 0.062）。QBA评分与任何生理指标均无相关性（P > 0.05）。还进行了受试者工作曲线（ROC）分析，以更好地了解生理措施在区分动物中的有用性，这些动物在其一生中记录了与福利相关的问题，而不是那些没有记录的问题。毛发皮质醇被确定为在区分农场被咬尾的猪与未被咬的猪方面具有“中等”准确性（AUC：0.748），而Hp和CRP被确定为没有有意义的区分能力（AUC < 0.600）。这项研究应该在更大范围内重复进行，但结果表明，屠宰时测量的毛发皮质醇可以深入了解猪一生中的福利状况。幽门螺杆菌可能是猪尾部病变的一个有用指标。然而，在得出结论之前，需要进一步研究使用更大比例的严重咬伤的猪。
Physiological measures indicative of the welfare status of animals during rearing could form part of an abattoir-based animal health and welfare assessment tool. A total of 66 pigs were used in this study, the aim of which was to assess how serum concentrations of haptoglobin (Hp) and C-reactive protein (CRP) (assessed in 51 pigs), and hair concentrations of cortisol (assessed in 65 pigs), measured at or close to slaughter, reflected welfare-related indicators recorded from the animal during its lifetime. These indicators were recorded at intervals between 7 and 21 weeks of age and included assigning scores for levels of tail and skin lesions, recording the presence or absence of certain health issues, and conducting qualitative behavioural assessments (QBA). Pigs recorded as having tail lesions during their lifetime had higher hair cortisol levels than those with no tail lesions (tail lesions: 47.87 ± 3.34 pg/mg, no tail lesions: 42.20 ± 3.29 pg/mg, P = 0.023), and pigs recorded as having moderate or severe tail lesions had higher Hp levels than those with no or mild tail lesions (moderate/severe: 1.711 mg/ml ± 0.74, none/mild: 0.731 mg/ml ±0.10, P = 0.010). Pigs recorded as being lame during their lifetime tended to have higher hair cortisol levels than non-lame pigs (lame: 52.72 pg/mg ± 3.83, not lame: 43.07 pg/mg ± 2.69, P = 0.062). QBA scores were not associated with any of the physiological measures (P > 0.05). Receiver Operator Curve (ROC) analysis was also carried out to get a better understanding of the usefulness of the physiological measures in discriminating animals that had had welfare-related issues recorded during their lifetime from those that had not. Hair cortisol was determined as having ‘moderate’ accuracy in discriminating pigs that were tail bitten on-farm from unbitten pigs (AUC: 0.748) while Hp and CRP were determined to have no meaningful discriminatory ability (AUC < 0.600). This research should be repeated on a larger scale, but the results suggest that hair cortisol measured at slaughter could provide insight into the welfare status of pigs during their lifetime. Hp may be a useful indicator of tail lesions in pigs. However, further research utilising a greater proportion of severely bitten pigs is required before conclusions can be drawn.
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影响因子：
2.6
作者：
Alarcon, Pablo;Wieland, Barbara;Dewberry, Chris
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