Minority report: the intestinal mycobiota in systemic infections.
Minority report: the intestinal mycobiota in systemic infections.
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少数族裔报告:全身感染中的肠道菌菌群。
DOI:
10.1016/j.mib.2020.05.004
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发表时间:
2020-08
影响因子:
5.4
通讯作者:
Zhai B
中科院分区:
文献类型:
--
作者:
Rolling T;Hohl TM;Zhai B
Compared to bacteria, fungi often exhibit a lower abundance and a higher temporal volatility in the intestinal microbiota. Analysis of fungi in the microbiota (mycobiota) faces technical limitations with tools that were originally developed for analyzing bacteria. Dysbiotic states of the intestinal mycobiota, often associated with disruption of the healthy bacterial microbiota, are characterized by overgrowth (domination) of specific fungal taxa and loss of diversity. Intestinal domination by Candida species has been shown to be a major source of Candida bloodstream infections. Fungal dysbiosis is also linked to the development and treatment response in non-fungal infections, for example Clostridioides difficile colitis and HIV. Further research is needed to define the contribution of intestinal mycobiota to human fungal and non-fungal infections.
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