Pexophagy in plants: a mechanism to remit cells from oxidative damage caused under high-intensity light
Pexophagy in plants: a mechanism to remit cells from oxidative damage caused under high-intensity light
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植物中的 Pexophagy：一种缓解细胞因高强度光引起的氧化损伤的机制
DOI：
10.1080/15548627.2023.2175570
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发表时间：
2023
期刊：
影响因子：
13.3
通讯作者：
M.
中科院分区：
文献类型：
--
作者：
Goto-Yamada;S.;Oikawa;K.;Hayashi Y.;Mano;S.;Yamada;S. and;Nishimura;M.
光对于植物生长至关重要，但过多的光能会产生活性氧（ROS），会严重损害细胞。 ATG（自噬相关）基因缺陷的突变体表现出光强度依赖性叶片损伤和 ROS 积累。我们发现自噬是通过去除氧化过氧化物酶体来保护植物免受 ROS 诱导的损伤的关键系统之一。受损的过氧化物酶体被 PtdIns3P 标记物靶向，并被 ATG18a-GFP 标记的吞噬细胞特异性吞噬。在高强度光下，巨大的过氧化物酶体聚集体被液泡膜诱导和捕获。研究使人们更深入地了解植物对光照射的胁迫反应。
Light is essential for plant growth, but excessive light energy produces reactive oxygen species (ROS), which can seriously damage cells. Mutants defective inATG(autophagy related) genes show light intensity-dependent leaf damage and ROS accumulation. We found that autophagy is one of the crucial systems in protecting plants from ROS-induced damage by removing oxidative peroxisomes. Damaged peroxisomes are targeted by the PtdIns3P marker and specifically engulfed by phagophores labeled by ATG18a-GFP. Under high-intensity light, huge peroxisome aggregates are induced and captured by vacuolar membranes. Research provides a deeper understanding of plant stress response to light irradiation.
影响因子：
16.6
作者：
Oikawa, Kazusato;Goto-Yamada, Shino;Hayashi, Yasuko;Takahashi, Daisuke;Kimori, Yoshitaka;Shibata, Michitaro;Yoshimoto, Kohki;Takemiya, Atsushi;Kondo, Maki;Hikino, Kazumi;Kato, Akira;Shimoda, Keisuke;Ueda, Haruko;Uemura, Matsuo;Numata, Keiji;Ohsumi, Yoshinori;Hara-Nishimura, Ikuko;Mano, Shoji;Yamada, Kenji;Nishimura, Mikio
通讯作者：
Nishimura, Mikio