Remembering nutrient quality of sugar in Drosophila.
Remembering nutrient quality of sugar in Drosophila.
复制标题
DOI:
10.1016/j.cub.2011.03.032
复制
发表时间:
2011-05-10
期刊:
影响因子:
9.2
通讯作者:
Waddell, Scott
中科院分区:
文献类型:
--
作者:
Burke, Christopher J.;Waddell, Scott
Taste is an early stage in food and drink selection for most animals. Detecting sweetness indicates the presence of sugar and possible caloric content. However, sweet taste can be an unreliable predictor of nutrient value because some sugars cannot be metabolized. In addition, discrete sugars are detected by the same sensory neurons in the mammalian and insect gustatory systems, making it difficult for animals to readily distinguish the identity of different sugars using taste alone. Here we used an appetitive memory assay in Drosophila to investigate the contribution of palatability and relative nutritional value of sugars to memory formation. We show that palatability and nutrient value both contribute to reinforcement of appetitive memory. Non-nutritious sugars formed less robust memory that could be augmented by supplementing with a tasteless but nutritious substance. Nutrient information is conveyed to the brain within minutes of training when it can be used to guide expression of a sugar-preference memory. Therefore flies can rapidly learn to discriminate between sugars using a post-ingestive reward evaluation system and they preferentially remember nutritious sugars.
登录
查看更多内容
DOI:
10.3791/193
发表时间:
2007-01-01
期刊:
Journal of visualized experiments : JoVE
影响因子:
--
作者:
Shiraiwa, Takashi;Carlson, John R
通讯作者:
Carlson, John R
影响因子:
16.2
作者:
Marella, S;Fischler, W;Scott, K
通讯作者:
Scott, K
影响因子:
5.3
作者:
Dotson, Cedrick D.;Spector, Alan C.
通讯作者:
Spector, Alan C.
影响因子:
5.5
作者:
Chambers, E. S.;Bridge, M. W.;Jones, D. A.
通讯作者:
Jones, D. A.
影响因子:
2.5
作者:
SIMPSON, SJ;WHITE, PR
通讯作者:
WHITE, PR