LIPID MAPS: update to databases and tools for the lipidomics community.
LIPID MAPS: update to databases and tools for the lipidomics community.
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DOI：
10.1093/nar/gkad896
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发表时间：
2024-01-05
影响因子：
14.9
通讯作者：
中科院分区：
文献类型：
--
作者：
LIPID MAPS（LIPID代谢和途径策略），www.lipidmaps.org，提供了组织脂质结构和生化数据的系统和标准化方法。成立于20年前，LIPID MAPS命名和分类已成为公认的社区标准。LIPID MAPS除了提供众多软件工具和教育资源外，还提供了用于编目和识别不同表征水平的脂质的数据库，并于2020年成为ELIXIR-UK数据资源。本文介绍了LIPID MAPS中现有数据库的扩展，包括更丰富的文献出处元数据、分类数据和改进的互操作性，以促进FAIR合规性。由ELIXIR-UK资助的一个联合项目与WikiPathways合作，策划和托管途径数据，并在其生化途径的背景下注释脂质。沿着描述了搜索基础结构的更新功能以及通过API和SPARQL实现的编程访问。已经开发了新的脂质特定数据库，并更新了向社区提供的脂质组学工具。通过网络研讨会、播客和在线培训学校扩大了培训和参与。
LIPID MAPS (LIPID Metabolites and Pathways Strategy), www.lipidmaps.org, provides a systematic and standardized approach to organizing lipid structural and biochemical data. Founded 20 years ago, the LIPID MAPS nomenclature and classification has become the accepted community standard. LIPID MAPS provides databases for cataloging and identifying lipids at varying levels of characterization in addition to numerous software tools and educational resources, and became an ELIXIR-UK data resource in 2020. This paper describes the expansion of existing databases in LIPID MAPS, including richer metadata with literature provenance, taxonomic data and improved interoperability to facilitate FAIR compliance. A joint project funded by ELIXIR-UK, in collaboration with WikiPathways, curates and hosts pathway data, and annotates lipids in the context of their biochemical pathways. Updated features of the search infrastructure are described along with implementation of programmatic access via API and SPARQL. New lipid-specific databases have been developed and provision of lipidomics tools to the community has been updated. Training and engagement have been expanded with webinars, podcasts and an online training school.
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