Activation deficit correlates with weakness in chronic stroke: evidence from evoked and voluntary EMG recordings.
Activation deficit correlates with weakness in chronic stroke: evidence from evoked and voluntary EMG recordings.
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DOI：
10.1016/j.clinph.2014.03.019
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发表时间：
2014-12
期刊：
影响因子：
--
通讯作者：
Rymer WZ
中科院分区：
文献类型：
--
作者：
Li S;Liu J;Bhadane M;Zhou P;Rymer WZ
使用诱发（M波）和随意（最大随意收缩（MVC）期间）肌电图记录来估计慢性卒中的随意激活水平。九名慢性轻偏瘫中风受试者参加了实验。记录肱二头肌的M波（EMGM-wave）和MVC（EMGMVC）EMG值。受损侧的峰值扭矩显著小于非受损侧。受损侧肌电图波形也明显小于非受损侧。然而，标准化的EMG波/TorqueMVC比值在两侧之间没有显著差异。相反，受损侧的绝对EMGMVC和标准化EMGMVC/TorqueMVC均小于非受损侧。自主激活水平，EMGMVC/M波，受损侧也小于非受损侧。受损侧的自主激活水平与无力高度相关（R=0.72），而非受损侧的自主激活水平非常低（R=0.32）。总的来说，我们的研究结果表明，外周和中枢因素都有助于中风后的弱点，但激活赤字与弱点最密切相关的估计，从最大的自愿扭矩产生。
To use evoked (M-wave) and voluntary (during maximal voluntary contraction (MVC)) EMG recordings to estimate the voluntary activation level in chronic stroke. Nine chronic hemiparetic stroke subjects participated in the experiment. M-wave (EMGM-wave) and MVC (EMGMVC) EMG values of the biceps brachii muscles were recorded. Peak torque was significantly smaller on the impaired than non-impaired side. EMGM-wave was also significantly smaller on the impaired than non-impaired side. However, the normalized EMGM-wave/TorqueMVC ratio was not significantly different between two sides. In contrast, both absolute EMGMVC and normalized EMGMVC/TorqueMVC were smaller on the impaired than non-impaired side. The voluntary activation level, EMGMVC/M-wave, was also smaller on the impaired than non-impaired side. The voluntary activation level on the impaired side was highly correlated with weakness (R=0.72), but very low (R=0.32) on the non-impaired side. Collectively, our findings suggest that both peripheral and central factors contribute to post-stroke weakness, but activation deficit correlates most closely with weakness as estimated from maximum voluntary torque generation.
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影响因子：
3
作者：
Fimland, Marius Steiro;Moen, Per Marius R.;Hill, Tessa;Gjellesvik, Tor Ivar;Torhaug, Tom;Helgerud, Jan;Hoff, Jan
通讯作者：
Hoff, Jan
DOI：
10.1097/phm.0b013e31824ad5b8
发表时间：
2012-05-01
影响因子：
3
作者：
Hill, Tessa R.;Gjellesvik, Tor Ivar;Hoff, Jan
通讯作者：
Hoff, Jan
影响因子：
1.1
作者：
Klein, Cliff S.;Power, Geoffrey A.;Rice, Charles L.
通讯作者：
Rice, Charles L.
DOI：
10.1016/j.apmr.2006.05.013
发表时间：
2006-09-01
影响因子：
4.3
作者：
Kamper, Derek G.;Fischer, Heidi C.;Rymer, William Z.
通讯作者：
Rymer, William Z.
DOI：
10.1038/nrneurol.2013.222
发表时间：
2013-12
期刊：
Nature reviews. Neurology
影响因子：
--
作者：
Small SL;Buccino G;Solodkin A
通讯作者：
Solodkin A