Assessment of the fetal lungs in utero.
Assessment of the fetal lungs in utero.
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DOI：
10.1016/j.ajogmf.2022.100693
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发表时间：
2022-09
影响因子：
6.3
通讯作者：
中科院分区：
文献类型：
--
作者：
近年来，由于影像学技术的进步，产前诊断肺发育异常的情况有了显著改善。二维超声是妊娠期间肺部病理检查的主要手段，在先天性膈疝等情况下提供良好的预后；然而，在其他高危人群中，如先天性肺气道畸形或早产早破膜者，其有效性较低。现在可以使用超声或磁共振成像对肺的体积和大小进行三维评估；然而，由于胎儿运动的不可预测，这些技术的使用仍然受到限制，而且这些工具在除先天性膈疝外的高危人群中也没有得到充分的验证。先进的功能性磁共振成像技术的出现，如扩散和T2*成像，以及便于运动校正的后处理管道的发展，不仅可以更准确地评估肺大小，还可以评估组织微观结构和灌注。在未来，胎儿磁共振成像可能在预测肺部异常和监测当前和未来的产前治疗中发挥越来越大的作用，以促进肺部发育。这篇综述的目的是检查目前可用于评估产前肺部发育的成像方法，并概述可能的未来发展方向。
Antenatal diagnosis of abnormal pulmonary development has improved significantly over recent years because of progress in imaging techniques. Two-dimensional ultrasound is the mainstay of investigation of pulmonary pathology during pregnancy, providing good prognostication in conditions such as congenital diaphragmatic hernia; however, it is less validated in other high-risk groups such as those with congenital pulmonary airway malformation or preterm premature rupture of membranes. Three-dimensional assessment of lung volume and size is now possible using ultrasound or magnetic resonance imaging; however, the use of these techniques is still limited because of unpredictable fetal motion, and such tools have also been inadequately validated in high-risk populations other than those with congenital diaphragmatic hernia. The advent of advanced, functional magnetic resonance imaging techniques such as diffusion and T2* imaging, and the development of postprocessing pipelines that facilitate motion correction, have enabled not only more accurate evaluation of pulmonary size, but also assessment of tissue microstructure and perfusion. In the future, fetal magnetic resonance imaging may have an increasing role in the prognostication of pulmonary abnormalities and in monitoring current and future antenatal therapies to enhance lung development. This review aims to examine the current imaging methods available for assessment of antenatal lung development and to outline possible future directions.
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影响因子：
3.7
作者：
Amodeo I;De Nunzio G;Raffaeli G;Borzani I;Griggio A;Conte L;Macchini F;Condò V;Persico N;Fabietti I;Ghirardello S;Pierro M;Tafuri B;Como G;Cascio D;Colnaghi M;Mosca F;Cavallaro G
通讯作者：
Cavallaro G
DOI：
10.1016/j.ejrnm.2014.11.015
发表时间：
2015-06-01
影响因子：
1
作者：
Behairy, Noha Hosam El Din;El Din, Lamiaa Adel Salah;Ali, Mohamed Abd El Kader
通讯作者：
Ali, Mohamed Abd El Kader
影响因子：
5.8
作者：
Corbett, Harriet J;Humphrey, Gillian M E
通讯作者：
Humphrey, Gillian M E
影响因子：
10.6
作者：
Alansary A;Rajchl M;McDonagh SG;Murgasova M;Damodaram M;Lloyd DFA;Davidson A;Rutherford M;Hajnal JV;Rueckert D;Kainz B
通讯作者：
Kainz B
影响因子：
7.1
作者：
Basurto, D.;Fuenzalida, J.;Gomez, O.
通讯作者：
Gomez, O.