Heterogeneity in perinatal depression: how far have we come? A systematic review.
Heterogeneity in perinatal depression: how far have we come? A systematic review.
复制标题
围产期抑郁症的异质性：我们已经走了多远？系统回顾。
DOI：
10.1007/s00737-016-0691-8
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发表时间：
2017-03
期刊：
影响因子：
--
通讯作者：
Salomon R
中科院分区：
文献类型：
--
作者：
Santos H Jr;Tan X;Salomon R
尽管围产期抑郁(PND)是一种影响孕妇和新妈妈的常见精神障碍，但人们对这种疾病的异质性关注有限。我们检查了PND症状特征和症状轨迹的异质性。文献检索共发现247项相关研究，其中23项纳入最终综述。用来研究症状和轨迹异质性的最常用的统计方法是潜伏类模型和生长混合模型。除一项研究外，所有研究都检查了PND症状轨迹，并提供了至少三种不同模式的集体证据：低、中或慢性-高度症状水平。社会和心理风险因素是与抑郁症状负担较高(总分高)相关的最常见的预测因素组。这些研究一致地报告了被分配到高负担症状轨迹的母亲的孩子的健康结果较差。只有一项研究探索了症状谱的异质性，并且是唯一一项描述与所确定的PND异质性模式相关的抑郁症状的特定星座的研究。因此，关于构成PND异质性的特定症状和症状配置的证据有限。我们提出了未来研究的方向，以进一步阐明PND的异质性及其相关机制。
Despite perinatal depression (PND) being a common mental disorder affecting pregnant women and new mothers, limited attention has been paid to the heterogeneous nature of this disorder. We examined heterogeneity in PND symptom profiles and symptom trajectories. Literature searches revealed 247 relevant studies, 23 of which were included in the final review. The most common statistical approaches used to explore symptom and trajectory heterogeneity were latent class model and growth mixture model. All but one study examined PND symptom trajectories, and provide collective evidence of at least three heterogeneous patterns: low, medium or chronic-high symptom levels. Social and psychological risk factors were the most common group of predictors related to a higher burden (high sum of score) of depressive symptoms. These studies were consistent in reporting poorer health outcomes for children of mothers assigned to high burden symptom trajectories. Only one study explored heterogeneity in symptom profile, and was the only one to describe the specific constellations of depressive symptoms related to the PND heterogeneous patterns identified. Therefore, there is limited evidence on the specific symptoms and symptom configurations that make up PND heterogeneity. We suggest directions for future research to further clarify the PND heterogeneity and its related mechanisms.
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影响因子：
7
作者：
Dziak JJ;Li R;Tan X;Shiffman S;Shiyko MP
通讯作者：
Shiyko MP
影响因子：
6.9
作者：
Cents, R. A. M.;Diamantopoulou, S.;Tiemeier, H.
通讯作者：
Tiemeier, H.
影响因子：
3.3
作者：
Glasheen, Cristie;Richardson, Gale A.;Day, Nancy L.
通讯作者：
Day, Nancy L.
DOI：
10.1146/annurev-clinpsy-050212-185608
发表时间：
2013-01-01
期刊：
ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 9
影响因子：
--
作者：
Borsboom, Denny;Cramer, Angelique O. J.
通讯作者：
Cramer, Angelique O. J.
影响因子：
3.6
作者：
Fried, Eiko I.;van Borkulo, Claudia D.;Borsboom, Denny
通讯作者：
Borsboom, Denny