Prepregnancy obesity and the racial disparity in infant mortality.
Prepregnancy obesity and the racial disparity in infant mortality.
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DOI：
10.1002/oby.21621
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发表时间：
2016-12
期刊：
影响因子：
6.9
通讯作者：
Bodnar, Lisa M.
中科院分区：
文献类型：
--
作者：
Lemon, Lara S.;Naimi, Ashley I.;Abrams, Barbara;Kaufman, Jay S.;Bodnar, Lisa M.
To estimate the extent to which prepregnancy obesity explains the Black-White disparity in stillbirth and infant mortality. A population-based study of linked Pennsylvania birth-infant death certificates (2003-2011; n=1,055,359 births) and fetal death certificates (2006-2011; n=3,102 stillbirths) for all singleton pregnancies in non-Hispanic (NH) White and NH Black women. Inverse probability weighted regression was used to estimate the role of prepregnancy obesity in explaining the race-infant/fetal death association. Compared with NH White women, NH Black women were more likely to be obese (≥30kg/m2) and experienced a higher rate of stillbirth (8.3 vs. 3.6 stillbirths per 1,000 liveborn and stillborn infants) and infant death (8.5 vs. 3.0 infant deaths per 1,000 livebirths). When the contribution of prepregnancy obesity was removed, the difference in risk between NH Blacks and NH Whites decreased from 6.2 (95% CI: 5.6, 6.7) to 5.5 (95% CI: 4.9, 6.2) excess stillbirths per 1,000 and 5.8 (95% CI: 5.3, 6.3) to 5.2 (95% CI: 4.7, 5.7) excess infant deaths per 1,000. For every 10,000 livebirths in Pennsylvania (2003 to 2011), six of the 61 excess infant deaths in NH Black women and 5 of the 44 excess stillbirths (2006-2011) were attributable to prepregnancy obesity.
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