RSCanner: rapid assessment and visualization of RNA structure content.
RSCanner: rapid assessment and visualization of RNA structure content.
复制标题
DOI:
10.1093/bioinformatics/btad111
复制
发表时间:
2023-03-01
期刊:
影响因子:
--
通讯作者:
中科院分区:
文献类型:
--
作者:
The increasing availability of RNA structural information that spans many kilobases of transcript sequence imposes a need for tools that can rapidly screen, identify, and prioritize structural modules of interest. We describe RNA Structural Content Scanner (RSCanner), an automated tool that scans RNA transcripts for regions that contain high levels of secondary structure and then classifies each region for its relative propensity to adopt stable or dynamic structures. RSCanner then generates an intuitive heatmap enabling users to rapidly pinpoint regions likely to contain a high or low density of discrete RNA structures, thereby informing downstream functional or structural investigation. RSCanner is freely available as both R script and R Markdown files, along with full documentation and test data (https://github.com/pylelab/RSCanner).
登录
查看更多内容
影响因子:
16
作者:
Huston NC;Wan H;Strine MS;de Cesaris Araujo Tavares R;Wilen CB;Pyle AM
通讯作者:
Pyle AM
影响因子:
5.4
作者:
Wan, Han;Adams, Rebecca L.;Lindenbach, Brett D.;Pyle, Anna Marie
通讯作者:
Pyle, Anna Marie
影响因子:
14.9
作者:
Akiyama BM;Graham ME;O Donoghue Z;Beckham JD;Kieft JS
通讯作者:
Kieft JS
影响因子:
14.8
作者:
Smola MJ;Rice GM;Busan S;Siegfried NA;Weeks KM
通讯作者:
Weeks KM
影响因子:
48
作者:
Siegfried, Nathan A.;Busan, Steven;Rice, Greggory M.;Nelson, Julie A. E.;Weeks, Kevin M.
通讯作者:
Weeks, Kevin M.