Age-related delay in information accrual for faces: evidence from a parametric, single-trial EEG approach.
Age-related delay in information accrual for faces: evidence from a parametric, single-trial EEG approach.
复制标题
DOI：
10.1186/1471-2202-10-114
复制
发表时间：
2009-09-09
期刊：
影响因子：
2.4
通讯作者：
Sekuler AB
中科院分区：
文献类型：
--
作者：
Rousselet GA;Husk JS;Pernet CR;Gaspar CM;Bennett PJ;Sekuler AB
在这项研究中，我们通过一种创新的单试验ERP方法量化了人脸处理时间过程中与年龄相关的变化。与以前研究中使用的分析不同，我们的方法不依赖于峰值测量，可以提供更敏感的处理延迟测量。年轻人和老年人（平均年龄22岁和70岁）在两张面孔之间执行非快速辨别任务。通过五个中间步骤，对这些人脸的相位谱进行参数化处理，以创建介于纯噪声（0%相位信息）和未失真信号（100%相位信息）之间的图像。行为75%的正确阈值平均较低，而最大准确率较高，年轻的观察者比年长的观察者。每个受试者的erp被输入到一个单试验一般线性回归模型中，以确定与图像结构变化相关的神经活动的变化。年龄相关的ERP差异最早出现在N170的时间窗。年龄较大的观察者对噪声的N170反应明显较强，但这种年龄差异随着相位信息的增加而减小。总体而言，操纵图像相位信息对年轻观察者的erp有更大的影响，这是使用分层建模方法量化的。重要的是，年轻人和老年人的视觉活动是由相同的刺激参数调节的。在多个刺激后时间点计算模型的拟合，以R2为指标。R2函数的时间过程显示，在刺激开始后120毫秒左右，老年观察者的处理速度明显变慢。这种与年龄相关的延迟随着时间的推移而增加，达到190毫秒左右的最大值，在这个延迟上，年轻的观察者比年长的观察者领先50毫秒左右。使用无组件的ERP分析，提供了视觉系统对图像结构敏感度的精确时间，目前的研究表明，年长的观察者比年轻的受试者积累面部信息的速度要慢。此外，N170在年长的观察者中似乎对面部不那么敏感。
In this study, we quantified age-related changes in the time-course of face processing by means of an innovative single-trial ERP approach. Unlike analyses used in previous studies, our approach does not rely on peak measurements and can provide a more sensitive measure of processing delays. Young and old adults (mean ages 22 and 70 years) performed a non-speeded discrimination task between two faces. The phase spectrum of these faces was manipulated parametrically to create pictures that ranged between pure noise (0% phase information) and the undistorted signal (100% phase information), with five intermediate steps. Behavioural 75% correct thresholds were on average lower, and maximum accuracy was higher, in younger than older observers. ERPs from each subject were entered into a single-trial general linear regression model to identify variations in neural activity statistically associated with changes in image structure. The earliest age-related ERP differences occurred in the time window of the N170. Older observers had a significantly stronger N170 in response to noise, but this age difference decreased with increasing phase information. Overall, manipulating image phase information had a greater effect on ERPs from younger observers, which was quantified using a hierarchical modelling approach. Importantly, visual activity was modulated by the same stimulus parameters in younger and older subjects. The fit of the model, indexed by R2, was computed at multiple post-stimulus time points. The time-course of the R2 function showed a significantly slower processing in older observers starting around 120 ms after stimulus onset. This age-related delay increased over time to reach a maximum around 190 ms, at which latency younger observers had around 50 ms time lead over older observers. Using a component-free ERP analysis that provides a precise timing of the visual system sensitivity to image structure, the current study demonstrates that older observers accumulate face information more slowly than younger subjects. Additionally, the N170 appears to be less face-sensitive in older observers.
登录
查看更多内容
影响因子：
2.6
作者：
Curran, T;Hills, A;Strauss, ME
通讯作者：
Strauss, ME
DOI：
10.1016/s0926-6410(01)00132-x
发表时间：
2002-04-01
期刊：
COGNITIVE BRAIN RESEARCH
影响因子：
--
作者：
Gehring, WJ;Knight, RT
通讯作者：
Knight, RT
影响因子：
1.8
作者：
Betts, Lisa R.;Sekuler, Allison B.;Bennett, Patrick J.
通讯作者：
Bennett, Patrick J.
影响因子：
3.7
作者：
Davis, Simon W.;Dennis, Nancy A.;Cabeza, Roberto
通讯作者：
Cabeza, Roberto
影响因子：
--
作者：
Bullier, J
通讯作者：
Bullier, J