Response to familiar faces, newly familiar faces, and novel faces as assessed by ERPs is intact in adults with autism spectrum disorders.
Response to familiar faces, newly familiar faces, and novel faces as assessed by ERPs is intact in adults with autism spectrum disorders.
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DOI：
10.1016/j.ijpsycho.2010.04.011
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发表时间：
2010-08
影响因子：
3
通讯作者：
Dawson, Geraldine
中科院分区：
文献类型：
--
作者：
Webb, Sara J.;Jones, Emily J. H.;Merkle, Kristen;Murias, Michael;Greenson, Jessica;Richards, Todd;Aylward, Elizabeth;Dawson, Geraldine
患有自闭症谱系障碍（ASD）的个体在社会功能方面存在广泛的障碍，其中可能包括处理和记忆面孔的问题。在这项研究中，我们研究了与身份加工相关的后ERP成分（P2，N250和Face-N400）和与早期面部加工相关的成分（P1和N170）是否在ASD中是非典型的。我们收集了ERP反应熟悉的重复的脸（熟悉），一个陌生的重复的脸（其他）和新的面孔（小说）在29个高功能的成人ASD和匹配的控制。对于这两个群体，P2和N250是敏感的重复（其他与小说）和个人熟悉（熟悉与其他），和脸N400是敏感的重复。成人ASD没有表现出显着的非典型处理的面孔熟悉和重复的ERP范式，尽管表现出显着较差的性能比控制的行为测试的面孔记忆。这项研究发现，没有证据表明早期面部身份处理是高功能ASD中面部识别缺陷的主要原因。
Individuals with autism spectrum disorders (ASD) have pervasive impairments in social functioning, which may include problems with processing and remembering faces. In this study, we examined whether posterior ERP components associated with identity processing (P2, N250 and face-N400) and components associated with early-stage face processing (P1 and N170) are atypical in ASD. We collected ERP responses to a familiar repeated face (Familiar), an unfamiliar repeated face (Other) and novel faces (Novels) in 29 high functioning adults with ASD and matched controls. For both groups, the P2 and N250 were sensitive to repetition (Other vs. Novels) and personal familiarity (Familiar vs. Other), and the face-N400 was sensitive to repetition. Adults with ASD did not show significantly atypical processing of facial familiarity and repetition in an ERP paradigm, despite showing significantly poorer performance than controls on a behavioral test of face memory. This study found no evidence that early-stage facial identity processing is a primary contributor to the face recognition deficit in high functioning ASD.
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