Quantitative sensory testing (QST) in the orofacial region of healthy Chinese: influence of site, gender and age
Quantitative sensory testing (QST) in the orofacial region of healthy Chinese: influence of site, gender and age
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健康中国人口面部的定量感觉测试（QST）：部位、性别和年龄的影响
DOI：
10.1080/00016357.2017.1383511
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发表时间：
2018-01
影响因子：
2
通讯作者：
Peter Svensson
中科院分区：
文献类型：
--
作者：
Wang Yanting;Mo Xueyin;Zhang Jinglu;Fan Yuan;Wang Kelun;Peter Svensson
摘要目的：采用标准化定量感觉测试（QST）建立初步的热感觉和机械感觉特征，以研究健康中国人的部位、性别和年龄差异。材料与方法：20岁以下（年龄：20-40岁，10名男性，10名女性）和20名年龄较大（年龄：41-61岁，10名男性，10名女性）的健康参与者完成了研究。在左手、两侧颏区、舌尖和下唇粘膜5个部位测定冷觉阈（CDT）、温觉阈（WDT）、冷痛阈（CPT）、热痛阈（HPT）、机械觉阈（MDT）和机械痛阈（MPT）。采用重复测量的混合模型方差分析对数据进行分析。结果：与心理区域相比，手部的MDT（p < .001）和MPT（p < .05）显著更高。与唇粘膜相比，舌的CDT（p = 0.006）显著较高，WDT（p <0.001）显著较低，舌粘膜的CDT（p <0.001）高于颏区。与颏区相比，舌尖和下唇粘膜的WDT（p <0.001）和HPT（p <0.05）显著更高。与年轻组相比，老年组对WDT（p <0.001）和CDT（p = 0.004）的敏感性显著降低。发现了显著的性别差异，与女性相比，男性对WDT（p = .024）和MDT（p = .003）的敏感性较低。结论：标准化QST可以提供中国人群口面躯体感觉表型的有价值的信息。年龄、性别和研究中心是强制性控制的。
Abstract Objective: To establish a preliminary thermal and mechanical somatosensory profile using a standardized quantitative sensory testing (QST) to investigate site, gender and age differences in healthy Chinese. Materials and methods: Twenty younger (age: 20–40 years, 10 men, 10 women) and twenty older (age: 41–61 years, 10 men, 10 women) healthy participants completed the study. Cold detection threshold (CDT), warm detection threshold (WDT), cold pain threshold (CPT), heat pain threshold (HPT), mechanical detection threshold (MDT) and mechanical pain threshold (MPT) were measured at five sites: Left hand, bilaterally at the mental area, tip of tongue and the lower lip mucosa. Mixed model ANOVAs with repeated measures were used to analyze the data. Results: MDT(p < .001) and MPT (p < .05) were significantly higher on the hand compared to the mental areas. The CDT ( p = .006) was significantly higher and WDT (p < .001) was significantly lower at the tongue compared to lip mucosa and CDT (p < .001) was higher at the tongue mucosa than at the mental areas. WDT (p < .001) and HPT (p < .05) were significantly higher at the tip of the tongue and the lower lip mucosa compared to the mental areas. Significantly lower sensitivity for WDT (p < .001) and CDT (p = .004) were found in the older group compared to the younger group. Significant gender differences were found with less sensitivity for WDT (p = .024) and MDT (p = .003) in men compared to women. Conclusions: Application of standardized QST can provide valuable information of orofacial somatosensory phenotypes in a Chinese population. Age, gender and site are mandatory to control for.
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DOI：
10.1159/isbn.978-3-318-04053-1
发表时间：
1992-08
期刊：
--
影响因子：
--
作者：
A. Light;R. C. Shults;Sharon L. Jones
通讯作者：
A. Light;R. C. Shults;Sharon L. Jones
影响因子：
--
作者：
P. Svensson;L. Baad‐Hansen;T. Thygesen;G. Juhl;T. Jensen
通讯作者：
P. Svensson;L. Baad‐Hansen;T. Thygesen;G. Juhl;T. Jensen
影响因子：
2.9
作者：
Baad-Hansen L;Pigg M;Yang G;List T;Svensson P;Drangsholt M
通讯作者：
Drangsholt M
DOI：
--
发表时间：
2015-06
影响因子：
--
作者：
Guang-ju Yang;Ye Cao;Lei Zhang;X. Qin;Q. Xie
通讯作者：
Guang-ju Yang;Ye Cao;Lei Zhang;X. Qin;Q. Xie
影响因子：
9.9
作者：
Goransson, LG;Mellgren, SI;Omdal, R
通讯作者：
Omdal, R