Relationship between total mechanical energy and oxygen consumption in the stunned myocardium.
Relationship between total mechanical energy and oxygen consumption in the stunned myocardium.
复制标题
顿挫心肌中总机械能与耗氧量之间的关系。
DOI：
10.1016/0003-4975(90)90299-l
复制
发表时间：
1990
期刊：
影响因子：
--
通讯作者：
EdmundsJr,LH
中科院分区：
文献类型：
--
作者：
Furukawa,S;Bavaria,JE;Kreiner,G;EdmundsJr,LH
本文研究了7只绵羊热缺血25分钟前后左心室耗氧量（LVVo_2）与心室总机械能产生（P-VA）的关系。比较LVVo 2与P-VA、LVVo 2与每搏作功、LVVo 2与收缩期应力积分的关系。使用所提出的方法，P-VA可以在体内测量（n = 123）在缺血前和缺血后的心脏。缺血使LVVo 2与P-VA、每搏作功与收缩期应力积分关系的斜率增大，使每搏作功的氧利用率降低到2%以下。LVVo 2与P-VA之间关系的决定系数一般高于LVVo 2与每搏功或收缩期应力积分之间的决定系数。我们的结论是，收缩期P-VA可以在体内测量使用最近开发的方法，它是适用于缺血后“休克”的心脏。由于P-VA和LVVo 2可以转换为相同的能量单位，因此计算P-VA可以计算心肌氧利用效率。
We studied the relationship between left ventricular oxygen consumption (LVVo2) and total ventricular mechanical energy production as determined by calculation of the systolic pressure-volume area (P-VA) before and after 25 minutes of warm ischemia in 7 sheep. We compared the relationship between LVVo2and P-VA with the relationships between LVVo2and stroke work and between LVVo2and the systolic stress integral. Using the methods presented, P-VA can be measured in vivo (n = 123) in both preischemic and postischemic hearts. Ischemia increases the slopes of the relationship between LVVo2and P-VA and between stroke work and the systolic stress integral, and reduces the oxygen utilization efficiency of stroke work to less than 2%. Coefficients of determination for the relationship between LVVo2and P-VA are, in general, higher than those between LVVo2and either stroke work or the systolic stress integral. We conclude that systolic P-VA can be measured in vivo using recently developed methods and that it is applicable to postischemic “stunned” hearts. Because P-VA and LVVo2can be converted into identical energy units, calculation of P-VA permits calculation of myocardial oxygen utilization efficiency.
登录
查看更多内容
影响因子：
4.6
作者：
MARKOVITZ, LJ;SAVAGE, EB;EDMUNDS, LH
通讯作者：
EDMUNDS, LH
影响因子：
15.9
作者：
BOLLI, R;PATEL, BS;MCCAY, PB
通讯作者：
MCCAY, PB
影响因子：
24
作者：
K. Przyklenk;R. Kloner
通讯作者：
K. Przyklenk;R. Kloner
DOI：
10.1152/ajpheart.1977.233.4.h421
发表时间：
1977
期刊：
The American journal of physiology
影响因子：
--
作者：
K. Weber;J. S. Janicki
通讯作者：
J. S. Janicki
DOI：
--
发表时间：
1990
期刊：
The Journal of thoracic and cardiovascular surgery
影响因子：
--
作者：
Bavaria,JE;Furukawa,S;Kreiner,G;Ratcliffe,MB;Streicher,J;Bogen,DK;EdmundsJr,LH
通讯作者：
EdmundsJr,LH