Prevalence of plasmodium, leptospira and rickettsia species in Northern Tanzania: a community based survey.
Prevalence of plasmodium, leptospira and rickettsia species in Northern Tanzania: a community based survey.
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DOI：
10.4314/ahs.v20i1.25
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发表时间：
2020-03
影响因子：
1
通讯作者：
Kapyolo EP
中科院分区：
文献类型：
--
作者：
Chilongola JO;Sabuni EJ;Kapyolo EP
疟疾、钩端螺旋体和立克次体感染的症状、地理和季节重叠，使疟疾诊断变得困难，增加了误诊的机会。缺乏关于疟原虫、钩端螺旋体和立克次体感染流行情况的数据，导致对疟疾的过度诊断。我们的目标是确定坦桑尼亚北部疟疾、钩端螺旋体和立克次体感染的流行和分布情况。在坦桑尼亚北部的两个地点进行了以社区为基础的横断面调查。用聚合酶链式反应检测疟原虫、钩端螺旋体和立克次体感染。恶性疟原虫和钩端螺旋体感染率分别为24.2%(31/128)和2.3%(3/128)。两个地点均未发现立克次体感染。从研究地点来看，在邦多，31/63(49.2%)的参与者感染了疟原虫，而在马古古，3/65(4.6%)的参与者检测到钩端螺旋体感染。马古古未检出疟原虫，邦多未检出钩端螺旋体感染。发热与疟原虫感染(χ2=12.44，p<；0.001)和年龄(χ2=17.44，p=0.000)显著相关。这项研究的结果表明，疟疾感染是研究地点发烧的主要原因。虽然疟原虫和钩端螺旋体会导致发烧，但立克次体感染是坦桑尼亚北部发烧的一个微不足道的原因。
The overlap of symptoms, geographic and seasonal co-occurrence of Plasmodium, Leptospira and Rickettsia infections makes malaria diagnosis difficult, increasing the chances of misdiagnosis. The paucity of data on the prevalence Plasmodium, Leptospira and Rickettsia infections contributes to an overly diagnosis of malaria. We aimed to determine the prevalence and distribution of Plasmodium, Leptospira and Rickettsia infections in northern Tanzania. A community based, cross sectional survey was conducted in two sites in Northern Tanzania. PCR was used to detect Plasmodium, Leptospira and Rickettsia infections. The prevalence of P. falciparum and Leptospira spp were 31/128 (24.2%) and 3/128 (2.3%), respectively. No Rickettsia infection was detected in any of the two sites. Taking study sites separately, Plasmodium infection was detected in 31/63(49.2%) of participants in Bondo while Leptospira infection was detected in 3/65(4.6%) of participants in Magugu. Plasmodium was not detected in Magugu while no Leptospira infections were detected in Bondo. Fever was significantly associated with Plasmodium infection (χ2= 12.44, p<0.001) and age (χ2=17.44, p=0.000). Results from this study indicate Plasmodium infection as the main cause of fever in the studied sites. While Plasmodium and Leptospira contribute to fevers, Rickettsia infection is an insignificant cause of fever in Northern Tanzania.
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使用基于医院的监测和坦桑尼亚的基于人群的医疗保健利用调查来估计钩端螺旋体病的发病率。
影响因子：
3.8
作者：
Biggs HM;Hertz JT;Munishi OM;Galloway RL;Marks F;Saganda W;Maro VP;Crump JA
通讯作者：
Crump JA
影响因子：
11.8
作者：
Mediannikov O;Socolovschi C;Edouard S;Fenollar F;Mouffok N;Bassene H;Diatta G;Tall A;Niangaly H;Doumbo O;Lekana-Douki JB;Znazen A;Sarih M;Ratmanov P;Richet H;Ndiath MO;Sokhna C;Parola P;Raoult D
通讯作者：
Raoult D
影响因子：
3
作者：
Bonner, Kimberly;Mwita, Alex;Brown, Nick
通讯作者：
Brown, Nick
影响因子：
3.2
作者：
Hildebrandt, Anke;Franke, Jan;Straube, Eberhard
通讯作者：
Straube, Eberhard
影响因子：
3.7
作者：
Socolovschi C;Pages F;Ndiath MO;Ratmanov P;Raoult D
通讯作者：
Raoult D