Enhanced expression of a protein antigen (JI‐31 antigen, 30 kilodaltons) by reactive astrocytes in lacerated spinal cord
Enhanced expression of a protein antigen (JI‐31 antigen, 30 kilodaltons) by reactive astrocytes in lacerated spinal cord
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撕裂脊髓中反应性星形胶质细胞增强蛋白质抗原（JI-31 抗原，30 千道尔顿）的表达
DOI：
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发表时间：
1988
影响因子：
4.2
通讯作者：
G. D. Das
中科院分区：
文献类型：
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作者：
R. Predy;S. Malhotra;G. D. Das
一种小鼠单克隆抗体IMAb JI‐31，同型IgG 2b针对多发性硬化症（MS）患者的脑白质尸检样本。单抗JI‐31识别人脑中分子量约为30,000道尔顿（30kd）的蛋白质（JI‐31抗原），通过免疫沉淀、SDS‐凝胶电泳（还原条件）和放射自显像测定（Singh等人：Biosci Rep 6:73-79,1986）。免疫荧光显微检查。单抗JI‐31可染色胶质原纤维酸性蛋白（GFAP）阳性细胞，即来自GFAP的星形胶质细胞（Predy等人：Biosci Rep:491 - 502,1987）。
A mouse monoclonal antibody IMAb JI‐31, isotype IgG 2b was raised against an autopsy sample of cerebral white matter from a multiple sclerosis (MS) patient. MAb JI‐31 recognizes a protein (JI‐31 antigen) in human brain which has a molecular weight of approximately 30,000 daltons (30 kD) as determined by immunoprecipitaion followed by SDS‐gel electrophoresis (reducing conditions) and autoradiography (Singh et al.: Biosci Rep 6:73–79,1986). By immunofluorescence micoroscopy,. Mab JI‐31 stains glial fibrillary acidic protein (GFAP)‐positive cells, namely astrocytes from GFAP (Predy et al.:Biosci Rep 7:491–502,1987).
DOI：
10.1073/pnas.83.4.1125
发表时间：
1986-02-01
影响因子：
11.1
作者：
IGNATIUS, MJ;GEBICKEHARTER, PJ;SHOOTER, EM
通讯作者：
SHOOTER, EM