Five-minute whole-heart coronary MRA with sub-millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D-PROST reconstruction.
Five-minute whole-heart coronary MRA with sub-millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D-PROST reconstruction.
复制标题
DOI：
10.1002/mrm.27354
复制
发表时间：
2019-01
影响因子：
3.3
通讯作者：
Prieto C
中科院分区：
文献类型：
--
作者：
Bustin A;Ginami G;Cruz G;Correia T;Ismail TF;Rashid I;Neji R;Botnar RM;Prieto C
通过将呼吸运动校正与高度加速可变密度采样相结合，并结合新型基于 3D 补片的欠采样重建 (3D-PROST)，在临床可行的扫描时间内实现具有各向同性亚毫米分辨率的全心 3D 冠状动脉磁共振血管造影 (CMRA)。欠采样的可变密度螺旋状笛卡尔轨迹与基于 2D 图像的导航器相结合，以实现 100% 的呼吸效率和可预测的扫描时间。 3D-PROST 重建通过稀疏表示整合来自 3D 斑块邻域的结构信息，从而以有效的低秩公式利用冠状动脉 3D 解剖结构的冗余。所提出的框架在静态分辨率模型和 10 名健康受试者中进行了评估，各向同性分辨率为 1.2mm3 和 0.9mm3，欠采样因子为 ×5 和 ×9。将 3D-PROST 与完全采样（仅 1.2mm3）、传统并行成像和压缩感知重建进行比较。体模和体内 (1.2mm3) 重建与参考完全采样图像非常一致。对于 0.9 mm3 分辨率，体内平均采集时间（分钟：秒）为 7:57±1:18 (×5) 和 4:35±0:44 (×9)。亚毫米 3D-PROST 能够出色地描绘左冠状动脉和右冠状动脉，包括小分支血管，与传统重建技术相比，血管清晰度和可见血管长度进一步提高。由 2 位专家评定的图像质量表明 3D-PROST 可以提供良好的图像质量，并且即使在高加速系数下也具有鲁棒性。所提出的方法能够在 <5 分钟内实现具有各向同性亚毫米分辨率的自由呼吸全心 3D CMRA，并在较短且可预测的扫描时间内实现改善的冠状动脉可视化。
To enable whole‐heart 3D coronary magnetic resonance angiography (CMRA) with isotropic sub‐millimeter resolution in a clinically feasible scan time by combining respiratory motion correction with highly accelerated variable density sampling in concert with a novel 3D patch‐based undersampled reconstruction (3D‐PROST). An undersampled variable density spiral‐like Cartesian trajectory was combined with 2D image‐based navigators to achieve 100% respiratory efficiency and predictable scan time. 3D‐PROST reconstruction integrates structural information from 3D patch neighborhoods through sparse representation, thereby exploiting the redundancy of the 3D anatomy of the coronary arteries in an efficient low‐rank formulation. The proposed framework was evaluated in a static resolution phantom and in 10 healthy subjects with isotropic resolutions of 1.2 mm3 and 0.9 mm3 and undersampling factors of ×5 and ×9. 3D‐PROST was compared against fully sampled (1.2 mm3 only), conventional parallel imaging, and compressed sensing reconstructions. Phantom and in vivo (1.2 mm3) reconstructions were in excellent agreement with the reference fully sampled image. In vivo average acquisition times (min:s) were 7:57 ± 1:18 (×5) and 4:35 ± 0:44 (×9) for 0.9 mm3 resolution. Sub‐millimeter 3D‐PROST resulted in excellent depiction of the left and right coronary arteries including small branch vessels, leading to further improvements in vessel sharpness and visible vessel length in comparison with conventional reconstruction techniques. Image quality rated by 2 experts demonstrated that 3D‐PROST provides good image quality and is robust even at high acceleration factors. The proposed approach enables free‐breathing whole‐heart 3D CMRA with isotropic sub‐millimeter resolution in <5 min and achieves improved coronary artery visualization in a short and predictable scan time.
登录
查看更多内容
影响因子：
37.8
作者：
Jansen, C. H. P.;Perera, D.;Botnar, R. M.
通讯作者：
Botnar, R. M.
影响因子：
3.3
作者：
Henningsson, Markus;Smink, Jouke;Botnar, Rene M.
通讯作者：
Botnar, Rene M.
影响因子：
14
作者：
Hamdan, Ashraf;Asbach, Patrick;Fleck, Eckart
通讯作者：
Fleck, Eckart
影响因子：
3.3
作者：
Moghari, Mehdi H.;Annese, David;Powell, Andrew J.
通讯作者：
Powell, Andrew J.
影响因子：
3.3
作者：
Akcakaya, Mehmet;Basha, Tamer A.;Goddu, Beth;Goepfert, Lois A.;Kissinger, Kraig V.;Tarokh, Vahid;Manning, Warren J.;Nezafat, Reza
通讯作者：
Nezafat, Reza