Vertebrate intestinal endoderm development.
Vertebrate intestinal endoderm development.
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DOI:
10.1002/dvdy.22540
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发表时间:
2011-03
期刊:
影响因子:
--
通讯作者:
Shroyer NF
中科院分区:
文献类型:
--
作者:
Spence JR;Lauf R;Shroyer NF
The endoderm gives rise to the lining of the esophagus, stomach and intestines, as well as associated organs. To generate a functional intestine, a series of highly orchestrated developmental processes must occur. In this review, we attempt to cover major events during intestinal development from gastrulation to birth, including endoderm formation, gut tube growth and patterning, intestinal morphogenesis, epithelial reorganization, villus emergence as well as proliferation and cytodifferentiation. Our discussion includes morphological and anatomical changes during intestinal development as well as molecular mechanisms regulating these processes.
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