Computational fluid dynamics investigation of human aspiration in low velocity air: orientation effects on nose-breathing simulations.
Computational fluid dynamics investigation of human aspiration in low velocity air: orientation effects on nose-breathing simulations.
复制标题
低速空气中人体吸气的计算流体动力学研究:鼻子呼吸模拟的方向效应。
DOI:
10.1093/annhyg/meu018
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发表时间:
2014
期刊:
影响因子:
--
通讯作者:
Anthony,TRenée
中科院分区:
文献类型:
--
作者:
Anderson,KimberlyR;Anthony,TRenée
An understanding of how particles are inhaled into the human nose is important for developing samplers that measure biologically relevant estimates of exposure in the workplace. While previous computational mouth-breathing investigations of particle aspiration have been conducted in slow moving air, nose breathing still required exploration. Computational fluid dynamics was used to estimate nasal aspiration efficiency for an inhaling humanoid form in low velocity wind speeds (0.1–0.4 m s−1). Breathing was simplified as continuous inhalation through the nose. Fluid flow and particle trajectories were simulated over seven discrete orientations relative to the oncoming wind (0, 15, 30, 60, 90, 135, 180°). Sensitivities of the model simplification and methods were assessed, particularly the placement of the recessed nostril surface and the size of the nose. Simulations identified higher aspiration (13% on average) when compared to published experimental wind tunnel data. Significant differences in aspiration were identified between nose geometry, with the smaller nose aspirating an average of 8.6% more than the larger nose. Differences in fluid flow solution methods accounted for 2% average differences, on the order of methodological uncertainty. Similar trends to mouth-breathing simulations were observed including increasing aspiration efficiency with decreasing freestream velocity and decreasing aspiration with increasing rotation away from the oncoming wind. These models indicate nasal aspiration in slow moving air occurs only for particles <100 µm.
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DOI:
10.1172/jci109760
发表时间:
1980
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
J. Smolen;H. Korchak;G. Weissmann
通讯作者:
G. Weissmann
DOI:
--
发表时间:
1984
期刊:
The Journal of laboratory and clinical medicine
影响因子:
--
作者:
Smolen,JE
通讯作者:
Smolen,JE
DOI:
--
发表时间:
1981
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Niewiarowski,S;Budzynski,AZ;Morinelli,TA;Brudzynski,TM;Stewart,GJ
通讯作者:
Stewart,GJ
DOI:
--
发表时间:
1970
期刊:
Biochemical Medicine
影响因子:
--
作者:
L. Dechatelet;M. Cooper
通讯作者:
M. Cooper
影响因子:
4.1
作者:
J. Hanoune;D. Stengel;M. Lacombe
通讯作者:
M. Lacombe