Crucial biological functions of CCL7 in cancer.
Crucial biological functions of CCL7 in cancer.
复制标题
CCL7 在癌症中的重要生物学功能
作者:
Liu Y;Cai Y;Liu L;Wu Y;Xiong X
Chemokine (C-C motif) ligand 7 (CCL7), a CC chemokine, is a chemotactic factor and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is widely expressed in multiple cell types and can participate in anti-inflammatory responses through binding to its receptors to mediate the recruitment of immune cells. Abnormal CCL7 expression is associated with certain immune diseases. Furthermore, CCL7 plays a pivotal role in tumorigenesis. CCL7 promotes tumor progression by supporting the formation of the tumor microenvironment and facilitating tumor invasion and metastasis, although some studies have suggested that CCL7 has tumor suppressor effects. In this review, we summarize the currently available information regarding the influence of CCL7 on tumors.
登录
查看更多内容
影响因子:
24.5
作者:
Ericksen RE;Rose S;Westphalen CB;Shibata W;Muthupalani S;Tailor Y;Friedman RA;Han W;Fox JG;Ferrante AW Jr;Wang TC
通讯作者:
Wang TC
影响因子:
11.2
作者:
De Monte, Lucia;Wormann, Sonja;Protti, Maria Pia
通讯作者:
Protti, Maria Pia
影响因子:
4.2
作者:
Cho, Yong Beom;Lee, Woo Yong;Lee, Kuhn Uk
通讯作者:
Lee, Kuhn Uk
影响因子:
2.8
作者:
Gonzalez, Alvaro;Garcia de Durango, Cira;Vidal-Vanaclocha, Fernando
通讯作者:
Vidal-Vanaclocha, Fernando
影响因子:
13.5
作者:
Fransvea, Emilia;Angelotti, Umberto;Giannelli, Gianluigi
通讯作者:
Giannelli, Gianluigi