A radiation hybrid map of 40 loci for the distal long arm of human chromosome 8.

A radiation hybrid map of 40 loci for the distal long arm of human chromosome 8.
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人类 8 号染色体远端长臂 40 个基因座的辐射杂交图谱。

DOI:
10.1101/gr.5.4.334
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发表时间:
1995
期刊:
影响因子:
7
通讯作者:
Leach,RJ
Leach,RJ
中科院分区:
生物学1区
文献类型:
--
作者:
Lewis,TB;Nelson,L;Ward,K;Leach,RJ

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We generated a panel of 97 radiation hybrids from the cell line GM10156B, which contains only human chromosome 8 in a Chinese hamster ovary cell line background. Statistical analysis of the cosegregation of markers in the 97 radiation hybrids was used to construct a physical map delineating the order and intermarker distance of 40 8q24 loci. Twenty-one loci were ordered with maximum likelihood ratios greater than 1000:1. A high level of consistency was seen between our RH map and the published genetic map, suggesting that our panel will be a valuable resource for the rapid mapping of markers derived from human chromosome 8.
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