Malaria real-time PCR: correlation with clinical presentation.

Malaria real-time PCR: correlation with clinical presentation.
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DOI:
10.1016/j.nmni.2015.02.004
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发表时间:
2015-05
影响因子:
4
通讯作者:
Greub, G.
Greub, G.
中科院分区:
其他
文献类型:
--
作者:
Dormond, L.;Jaton, K.;de Valliere, S.;Genton, B.;Greub, G.

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在112例仅感染恶性疟原虫的患者中,将WHO的严重程度标准与通过显微镜和定量PCR评估的寄生虫负荷进行了比较。通过显微镜(p < 0.001)和PCR(p < 0.001)测定,临床严重程度与较高的寄生虫载量显著相关。因此,定量PCR可能有助于预测结果。
Among 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.001). Hence, quantitative PCR might be useful to predict outcome.
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