HeartMate left ventricular assist devices: a multigeneration of implanted blood pumps.
HeartMate left ventricular assist devices: a multigeneration of implanted blood pumps.
复制标题
HeartMate 左心室辅助装置：多代植入式血泵。
作者：
T. Maher;K. Butler;V. Poirier;D. Gernes
由Thermo Systems，Inc.开发的HeartMate系列植入式左心室辅助装置（LVAD）。(TCI)其时间范围可以追溯到机械循环支持的临床应用的开始，并将延伸到可预见的未来。HeartMates采用的相关血泵技术从最初的推板概念到最先进的旋转泵设备。从最初的气动推板泵开始，HeartMate I于1986年开始临床使用。1990年，电动马达驱动版本的HeartMate I开始在临床上使用。目前，HeartMate I已被植入全球约2，300名患者体内，该LVAD是目前所有其他LVAD的测量标准。继HeartMate I之后是TCI的下一代HeartMate II，这是一种基于旋转泵的LVAD，使用具有血液浸没机械轴承的轴流式血泵。HeartMate II的临床试验始于2000年。代表TCI下一代LVAD的HeartMate III围绕使用磁悬浮旋转组件的离心血泵构建。与HeartMate II相比，HeartMate III具有更高的整体效率。泵的工作寿命不取决于轴承磨损。鉴于以HeartMates II和III为代表的先进LVAD技术，加上HeartMate I的经验，TCI已做好准备，使其LVAD产品在未来成为行业标准。
The HeartMate family of implanted left ventricular assist devices (LVADs) developed by Thermo Cardiosystems, Inc. (TCI) span a time frame that goes back to the beginning of clinical use of mechanical circulatory support and will stretch well into the foreseeable future. Associated blood pump technology employed in the HeartMates range from an original pusher plate concept to the most advanced rotary pump devices. Starting initially with a pneumatic actuated pusher plate pump, clinical use of the HeartMate I began in 1986. In 1990, electric motor-actuated versions of the HeartMate I began to be used clinically. Presently, the HeartMate I has been implanted in some 2,300 patients worldwide, and this LVAD is a standard by which all others are currently measured. Following the HeartMate I is TCI's next-generation, the HeartMate II, a rotary-pump-based LVAD that uses an axial flow blood pump having blood immersed mechanical bearings. Clinical trials of the HeartMate II were initiated in 2000. The HeartMate III, representing TCI's next-generation LVAD, is structured around a centrifugal blood pump that uses a magnetically levitated rotating assembly. Compared to the HeartMate II, the HeartMate III has the potential for higher overall efficiency. The pump's operating life is not dependent on bearing wear. Given the significantly advanced LVAD technology represented by HeartMates II and III, coupled with the experience of HeartMate I, TCI is well-poised to keep its LVAD products as industry standards in the future.
Nimbus/匹兹堡大学创新心室辅助系统的开发。
DOI：
10.1016/s0003-4975(99)00582-2
发表时间：
1999
期刊：
The Annals of thoracic surgery
影响因子：
--
作者：
Butler,KC;Dow,JJ;Litwak,P;Kormos,RL;Borovetz,HS
通讯作者：
Borovetz,HS