Cellular dynamics in the early mouse embryo: from axis formation to gastrulation.

Cellular dynamics in the early mouse embryo: from axis formation to gastrulation.
复制标题

DOI:
10.1016/j.gde.2010.05.008
复制
发表时间:
2010-08
影响因子:
4
通讯作者:
Hadjantonakis, Anna-Katerina
Hadjantonakis, Anna-Katerina
中科院分区:
生物学2区
文献类型:
--
作者:
Nowotschin, Sonja;Hadjantonakis, Anna-Katerina

文献摘要

参考文献

被引文献

相似文献

协调的细胞运动和相互的组织相互作用指导了最终胚层的形成和小鼠胚胎主要轴的发育。遗传学和胚胎学研究已经确定了介导这些形态发生过程的主要分子途径,并提供了形态发生程序的“快照”。然而,越来越清楚的是,这一基础需要验证,并且可以使用实时成像方法显着改进和扩展。活体标本中这些过程的原位可视化是一个主要目标,因为它提供了个体细胞行为的前所未有的细节,这些细节转化为塑造胚胎的大规模组织重排。
Coordinated cell movements and reciprocal tissue interactions direct the formation of the definitive germ layers and the elaboration of the major axes of the mouse embryo. Genetic and embryological studies have defined the major molecular pathways that mediate these morphogenetic processes and provided “snapshots” of the morphogenetic program. However it is increasingly clear that this foundation needs to be validated, and can be significantly refined and extended using live imaging approaches. In situ visualization of these processes in living specimens is a major goal, as it provides unprecedented detail of the individual cellular behaviors, which translate into the large-scale tissue rearrangements that shape the embryo.
DOI: 10.1186/1471-213x-9-54
发表时间: 2009-10-22
影响因子: --
作者:
Costello I;Biondi CA;Taylor JM;Bikoff EK;Robertson EJ
通讯作者: Robertson EJ
DOI: 10.1038/11932
发表时间: 1999-08-01
期刊: NATURE GENETICS
影响因子: 30.8
作者:
Liu, PT;Wakamiya, M;Bradley, A
通讯作者: Bradley, A
DOI: 10.1128/mcb.21.23.8184-8188.2001
发表时间: 2001-12-01
影响因子: 5.3
作者:
Carver, EA;Jiang, RL;Gridley, T
通讯作者: Gridley, T
DOI: 10.1016/j.devcel.2005.09.011
发表时间: 2005-11-01
期刊: DEVELOPMENTAL CELL
影响因子: 11.8
作者:
Kimura-Yoshida, C;Nakano, H;Matsuo, I
通讯作者: Matsuo, I
DOI: 10.1038/35000034
发表时间: 2000-02-01
影响因子: 21.3
作者:
Batlle, E;Sancho, E;de Herreros, AG
通讯作者: de Herreros, AG