Clinical performance of contrast enhanced abdominal pediatric MRI with fast combined parallel imaging compressed sensing reconstruction.
Clinical performance of contrast enhanced abdominal pediatric MRI with fast combined parallel imaging compressed sensing reconstruction.
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DOI：
10.1002/jmri.24333
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发表时间：
2014-07
影响因子：
4.4
通讯作者：
Vasanawala, Shreyas S.
中科院分区：
文献类型：
--
作者：
Zhang, Tao;Chowdhury, Shilpy;Lustig, Michael;Barth, Richard A.;Alley, Marcus T.;Grafendorfer, Thomas;Calderon, Paul D.;Robb, Fraser J. L.;Pauly, John M.;Vasanawala, Shreyas S.
将并行成像压缩传感与线圈压缩相结合的方法应用于临床，实现快速图像重建，并评估其在增强腹部儿童磁共振成像中的临床表现。在IRB批准和知情患者同意/同意的情况下，29名儿科患者被连续招募。在3T扫描仪上使用专用32通道儿科线圈和3D SPGR序列采集动态对比增强MRI，在高加速度(R=7.2)下采用伪随机欠采样。采用三种方法对欠采样数据进行重建：传统的并行成像方法和有无线圈压缩的组合并行成像压缩传感方法。这三组图像由两名放射科医生在同一地点进行独立和盲法评估，以获得整体图像质量和解剖结构的勾画。采用Wilcoxon检验检验评价结果无显著差异的假设，并分析观察者间的一致性。采用线圈压缩的快速重建不会降低图像质量。快速重建的结构描绘平均得分为4.1分，明显优于传统平行成像的平均得分3.1分(P<；0.05)。在结构划界评估方面，观察员之间达成了公平到实质性的协议。一种快速组合并行成像压缩传感方法在儿科临床环境中是可行的。初步结果表明，与平行成像相比，它可能会改善结构描绘。
To deploy clinically, a combined parallel imaging compressed sensing method with coil compression that achieves a rapid image reconstruction, and assess its clinical performance in contrast-enhanced abdominal pediatric MRI. With IRB approval and informed patient consent/assent, 29 consecutive pediatric patients were recruited. Dynamic contrast-enhanced MRI was acquired on a 3T scanner using a dedicated 32-channel pediatric coil and a 3D SPGR sequence, with pseudo-random undersampling at a high acceleration (R=7.2). Undersampled data were reconstructed with three methods: a traditional parallel imaging method and a combined parallel imaging compressed sensing method with and without coil compression. The three sets of images were evaluated independently and blindly by two radiologists at one siting, for overall image quality and delineation of anatomical structures. Wilcoxon tests were performed to test the hypothesis that there was no significant difference in the evaluations, and inter-observer agreement was analyzed. Fast reconstruction with coil compression did not deteriorate image quality. The mean score of structural delineation of the fast reconstruction was 4.1 on a 5-point scale, significantly better (P<0.05) than traditional parallel imaging (mean score 3.1). Fair to substantial inter-observer agreement was reached in structural delineation assessment. A fast combined parallel imaging compressed sensing method is feasible in a pediatric clinical setting. Preliminary results suggest it may improve structural delineation over parallel imaging.
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