Comparison of amide proton transfer imaging with perfusion imaging of using arterial spin-labeling for evidence of tumor invasion in glioblastoma
Comparison of amide proton transfer imaging with perfusion imaging of using arterial spin-labeling for evidence of tumor invasion in glioblastoma
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酰胺质子转移成像与动脉自旋标记灌注成像作为胶质母细胞瘤肿瘤侵袭证据的比较
DOI:
10.1016/j.inat.2021.101461
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发表时间:
2022
期刊:
影响因子:
--
通讯作者:
Kikuta Ken-ichiro
中科院分区:
文献类型:
--
作者:
Yamauchi Takahiro;Kitai Ryuhei;Kodera Toshiaki;Arishima Hidetaka;Matsuda Ken;Isozaki Makoto;Ishida Shota;Matta Yuki;Kanamoto Masayuki;Kimura Hirohiko;Kikuta Ken-ichiro
In glioblastoma, differentiation between cerebral edema and tumor infiltration is an important clinical question. Amide proton transfer (APT) and cerebral blood flow (CBF) are useful for evaluating the tumor invasion. In this case series, arterial spin-labeling (ASL)-CBF and APT were compared to determine which method was superior for predicting tumor infiltration in glioblastomas. Twelve specimens from 4 glioblastoma patients with confirmed selective sampling were obtained. APT signal intensity (SI) showed a strong correlation with cell density (R = 0.905;P< 0.0001). ASL-CBF showed no correlation with cell density (R = 0.373;P= 0.2319) but a correlation with vessel density (R = 0.724;P= 0.0077). In linear regression analysis, APT SI showed a positive relationship with cell density (R2= 0.819,P< 0.0001, linear regression; y = 30.70 + 6.24E-3*x). In glioblastoma, APT imaging may be superior for predicting tumor invasion than ASL-CBF.
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影响因子:
1.6
作者:
Qian Xu;Qi Liu;H. Ge;Xinting Ge;Jiangfen Wu;J. Qu;K. Xu
通讯作者:
K. Xu
DOI:
10.1016/j.ejca.2017.06.009
发表时间:
2017-09
期刊:
European journal of cancer (Oxford, England : 1990)
影响因子:
--
作者:
Jiang S;Eberhart CG;Zhang Y;Heo HY;Wen Z;Blair L;Qin H;Lim M;Quinones-Hinojosa A;Weingart JD;Barker PB;Pomper MG;Laterra J;van Zijl PCM;Blakeley JO;Zhou J
通讯作者:
Zhou J
影响因子:
3.5
作者:
Noguchi, T.;Yoshiura, T.;Honda, H.
通讯作者:
Honda, H.
影响因子:
2.7
作者:
Ye, Jing;Bhagat, Santosh Kumar;Yang, Guomei
通讯作者:
Yang, Guomei