Integrating pathomics with radiomics and genomics for cancer prognosis: A brief review.

Integrating pathomics with radiomics and genomics for cancer prognosis: A brief review.
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DOI:
10.21147/j.issn.1000-9604.2021.05.03
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发表时间:
2021-10-31
期刊:
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu
影响因子:
--
通讯作者:
Liu Z
Liu Z
中科院分区:
其他
文献类型:
--
作者:
Lu C;Shiradkar R;Liu Z

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在过去的十年中,计算病理学研究界的重点已经从复制病理学检查的诊断病理学家解锁和发现“亚视觉”的预后图像线索从组织病理学图像。虽然我们在数字病理学方面获得了更多的知识和经验,但新兴的目标是整合其他组学或模式,这将有助于建立更好的预后分析。在本文中,我们提供了一个简短的审查代表性的作品,重点是整合病理组学与放射组学和基因组学的癌症预后。包括:病理组学与基因组学的关联、病理组学与基因组学的融合、病理组学与放射组学的融合。我们还提出了挑战,潜在的机会和未来工作的途径。
In the last decade, the focus of computational pathology research community has shifted from replicating the pathological examination for diagnosis done by pathologists to unlocking and discovering “sub-visual” prognostic image cues from the histopathological image. While we are getting more knowledge and experience in digital pathology, the emerging goal is to integrate other-omics or modalities that will contribute for building a better prognostic assay. In this paper, we provide a brief review of representative works that focus on integrating pathomics with radiomics and genomics for cancer prognosis. It includes: correlation of pathomics and genomics; fusion of pathomics and genomics; fusion of pathomics and radiomics. We also present challenges, potential opportunities, and avenues for future work.
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