Structure and function of rhodopsins from solid state NMR and resonance Raman spectroscopy of isotopic retinal derivatives.
Structure and function of rhodopsins from solid state NMR and resonance Raman spectroscopy of isotopic retinal derivatives.
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来自同位素视网膜衍生物的固态核磁共振和共振拉曼光谱的视紫红质的结构和功能。
DOI：
10.1016/0968-0004(88)90181-8
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发表时间：
1988
影响因子：
13.8
通讯作者：
Herzfeld,J
中科院分区：
文献类型：
--
作者：
Lugtenburg,J;Mathies,RA;Griffin,RG;Herzfeld,J
© 1988. Elsevier Publications Cambridge 0376-5067188/$02.00 rhodopsins are a major class of biological pigments which contain the polyene vitamin A bound within an intrinsic membrane protein. Rhodopsins include both signal transducers (rhodopsin, iodopsin, porphyropsin and sensory rhodopsin) and energy transducers (bacte. riorhodopsin and halorhodopsin) which are found in mammals, invert6t~ Tates and bacteria I. Specific isotopic labeling of the retinal prosthetic group has now made it possible to study the structure and function of these pigments in exquisite detail with laser resonance Raman scattering and solid-state nuclear magnetic resonance (NMR) spectroscopy.The visual pigment rhodopsin, found in the disk membranes of retinal rod outer segments, contains an ll-cis retinal chromophore bound to Lys296 via a protonated Schiff base linkage 2. Upon absorption of light the chromophore photoisomerizes to the all-trans isomer, forming an energy-rich photoproduct called bathorhodopsin (see Fig. la). Subsequent decay to metarhodopsin II initiates a cyclic nucleotide cascade that leads to the closure of Na+ channels in the plasma membrane of the retinal rod cell and the generation of visual sensation 3. Bacteriorhodopsin (BR), the photoreactive protein in the purple mem-
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细菌感觉视紫红质和细菌视紫红质中发色团/蛋白质的相互作用。
影响因子：
3.4
作者：
Spudich,JL;McCain,DA;Nakanishi,K;Okabe,M;Shimizu,N;Rodman,H;Honig,B;Bogomolni,RA
通讯作者：
Bogomolni,RA
盐细菌的视紫红质样色素：古细菌中的光能和信号传感器。
影响因子：
13.8
作者：
Stoeckenius,W
通讯作者：
Stoeckenius,W
光生物和光化学瞬态的时间分辨共振拉曼光谱
影响因子：
18.3
作者：
J. Terner;M. El
通讯作者：
M. El
DOI：
--
发表时间：
1979
期刊：
影响因子：
--
作者：
B. Honig;U. Dinur;K. Nakanishi;V. Balogh‐Nair;M. Gawinowicz;M. Arnaboldi;M. Motto
通讯作者：
M. Motto
13C标记视黄醛的合成
DOI：
--
发表时间：
1985
期刊：
影响因子：
--
作者：
J. Lugtenburg
通讯作者：
J. Lugtenburg