Potential role of the bovine rumen microbiome in modulating milk composition and feed efficiency.
Potential role of the bovine rumen microbiome in modulating milk composition and feed efficiency.
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DOI：
10.1371/journal.pone.0085423
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Mizrahi I
中科院分区：
文献类型：
--
作者：
Jami E;White BA;Mizrahi I
反刍动物完全依赖于它们的微生物群来消化饲料，因此，它们的生存能力。因此，很容易假设常驻瘤胃细菌类群的组成和丰度与宿主的生理参数之间存在联系。利用焦磷酸测序方法，我们的特点是瘤胃细菌群落组成的15头奶牛和他们的生理参数。我们分析了不同动物之间的差异程度，发现一些生理参数（例如产奶量和成分）与瘤胃微生物组中各种细菌成员的丰度高度相关。一个明显的发现是厚壁菌门和拟杆菌门的比例与乳脂产量之间有很强的相关性。这些发现与人类研究结果一致，显示出随着拟杆菌的增加，肥胖增加的类似趋势。这种相关性在属的水平上仍然很明显，其中几个属与动物的生理参数相关。这表明细菌群落在塑造宿主生理参数方面具有作用。对这一过程的深入了解可能使我们能够通过细菌群落设计来调节瘤胃微生物组，以获得更好的农业产量。
Ruminants are completely dependent on their microbiota for feed digestion and consequently, their viability. It is therefore tempting to hypothesize a connection between the composition and abundance of resident rumen bacterial taxa and the physiological parameters of the host. Using a pyrosequencing approach, we characterized the rumen bacterial community composition in 15 dairy cows and their physiological parameters. We analyzed the degree of divergence between the different animals and found that some physiological parameters, such as milk yield and composition, are highly correlated with the abundance of various bacterial members of the rumen microbiome. One apparent finding was a strong correlation between the ratio of the phyla Firmicutes to Bacteroidetes and milk-fat yield. These findings paralleled human studies showing similar trends of increased adiposity with an increase in Bacteroidetes. This correlation remained evident at the genus level, where several genera showed correlations with the animals' physiological parameters. This suggests that the bacterial community has a role in shaping host physiological parameters. A deeper understanding of this process may allow us to modulate the rumen microbiome for better agricultural yield through bacterial community design.
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影响因子：
4.4
作者：
Hernandez-Sanabria, Emma;Guan, Le Luo;Leon-Quintero, Monica C.
通讯作者：
Leon-Quintero, Monica C.
DOI：
10.1126/science.1241214
发表时间：
2013-09-06
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Ridaura VK;Faith JJ;Rey FE;Cheng J;Duncan AE;Kau AL;Griffin NW;Lombard V;Henrissat B;Bain JR;Muehlbauer MJ;Ilkayeva O;Semenkovich CF;Funai K;Hayashi DK;Lyle BJ;Martini MC;Ursell LK;Clemente JC;Van Treuren W;Walters WA;Knight R;Newgard CB;Heath AC;Gordon JI
通讯作者：
Gordon JI
影响因子：
64.8
作者：
Arumugam, Manimozhiyan;Raes, Jeroen;Pelletier, Eric;Le Paslier, Denis;Yamada, Takuji;Mende, Daniel R.;Fernandes, Gabriel R.;Tap, Julien;Bruls, Thomas;Batto, Jean-Michel;Bertalan, Marcelo;Borruel, Natalia;Casellas, Francesc;Fernandez, Leyden;Gautier, Laurent;Hansen, Torben;Hattori, Masahira;Hayashi, Tetsuya;Kleerebezem, Michiel;Kurokawa, Ken;Leclerc, Marion;Levenez, Florence;Manichanh, Chaysavanh;Nielsen, H. Bjorn;Nielsen, Trine;Pons, Nicolas;Poulain, Julie;Qin, Junjie;Sicheritz-Ponten, Thomas;Tims, Sebastian;Torrents, David;Ugarte, Edgardo;Zoetendal, Erwin G.;Wang, Jun;Guarner, Francisco;Pedersen, Oluf;de Vos, Willem M.;Brunak, Soren;Dore, Joel;Weissenbach, Jean;Ehrlich, S. Dusko;Bork, Peer
通讯作者：
Bork, Peer
影响因子：
5
作者：
Stevenson, David M.;Weimer, Paul J.
通讯作者：
Weimer, Paul J.
影响因子：
3.7
作者：
Jami E;Mizrahi I
通讯作者：
Mizrahi I