Rapid urine antigen testing for Streptococcus pneumoniae in adults with community-acquired pneumonia: clinical use and barriers.

Rapid urine antigen testing for Streptococcus pneumoniae in adults with community-acquired pneumonia: clinical use and barriers.
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DOI:
10.1016/j.diagmicrobio.2014.05.008
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发表时间:
2014-08
影响因子:
2.9
通讯作者:
Moore MR
Moore MR
中科院分区:
医学4区
文献类型:
--
作者:
Harris AM;Beekmann SE;Polgreen PM;Moore MR

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肺炎链球菌(肺炎球菌)是成人社区获得性肺炎(CAP)最常见的细菌病因,是导致死亡的主要原因。大多数肺炎球菌CAP是通过血培养诊断的,这可能低估了疾病的负担。2007年CAP指南建议常规使用快速肺炎球菌尿抗原(UAg)检测。为了评估肺炎球菌UAg检测在住院成人CAP患者中的使用情况以及限制其使用的障碍,2013年向美国传染病学会新兴传染病网络的1287名传染病医生成员分发了一项基于网络的调查。在493个合格的反应中,65%使用肺炎球菌UAg测试。UAg使用的主要障碍是可用性(46%)。UAg使用者报告说,订购其他诊断测试和定制抗生素治疗较少。增加UAg检测可改善肺炎管理和肺炎球菌CAP监测。
Streptococcus pneumoniae (pneumococcus) is the most common bacterial etiology of community-acquired pneumonia (CAP) in adults, a leading cause of death. The majority of pneumococcal CAP is diagnosed by blood culture, which likely underestimates the burden of disease. The 2007 CAP guidelines recommend routine use of the rapid pneumococcal urinary antigen (UAg) test. To assess the how pneumococcal UAg testing is being used among hospitalized adult CAP patients and what barriers restrict its use, a Web-based survey was distributed in 2013 to 1287 infectious disease physician members of the Emerging Infectious disease Network of the Infectious Disease Society of America. Of 493 eligible responses, 65% use the pneumococcal UAg test. The primary barrier to UAg use was availability (46%). UAg users reported ordering fewer other diagnostic tests and tailoring antibiotic therapy. Increased access to UAg tests could improve pneumonia management and pneumococcal CAP surveillance.
DOI: 10.1371/journal.pone.0060273
发表时间: 2013
期刊: PloS one
影响因子: 3.7
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Said MA;Johnson HL;Nonyane BA;Deloria-Knoll M;O'Brien KL;AGEDD Adult Pneumococcal Burden Study Team;Andreo F;Beovic B;Blanco S;Boersma WG;Boulware DR;Butler JC;Carratalà J;Chang FY;Charles PG;Diaz AA;Domínguez J;Ehara N;Endeman H;Falcó V;Falguera M;Fukushima K;Garcia-Vidal C;Genne D;Guchev IA;Gutierrez F;Hernes SS;Hoepelman AI;Hohenthal U;Johansson N;Kolek V;Kozlov RS;Lauderdale TL;Mareković I;Masiá M;Matta MA;Miró Ò;Murdoch DR;Nuermberger E;Paolini R;Perelló R;Snijders D;Plečko V;Sordé R;Strålin K;van der Eerden MM;Vila-Corcoles A;Watt JP
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发表时间: 2014-04
期刊: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
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发表时间: 2005-06-01
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