The use of stable xenon-enhanced computed tomographic studies of cerebral blood flow to define changes in cerebral carbon dioxide vasoresponsivity caused by a severe head injury.
The use of stable xenon-enhanced computed tomographic studies of cerebral blood flow to define changes in cerebral carbon dioxide vasoresponsivity caused by a severe head injury.
复制标题
使用稳定的氙气增强计算机断层扫描研究脑血流来确定严重头部损伤引起的脑二氧化碳血管反应性的变化。
DOI:
10.1097/00006123-199112000-00011
复制
发表时间:
1991
期刊:
影响因子:
4.8
通讯作者:
Bouma,GJ
中科院分区:
文献类型:
--
作者:
Marion,DW;Bouma,GJ
Previous studies using the xenon-133 cerebral blood flow (CBF) method have documented the impairment of CO 2 vasoresponsivity after a severe head injury, but only global values can be obtained reliably with this technique. We studied CO 2 vasoresponsivity using the stable xenon-enhanced computed tomographic CBF method, which provided information about well-defined cortical regions and deep brain structures not available with the xenon-133 method. In 17 patients with admission Glasgow Coma Scale scores of 8 or less, hemispheric CO 2 vasoresponsivity ranged from 1.3 to 8.5% per mm Hg change in partial CO 2 pressure. Lobar, cerebellar, basal ganglia, and brain stem CO 2 vasoresponsivity frequently varied from the mean global value by more than 25%. In all but one patient, local CO 2 vasoresponsivity in one or more of these areas differed from the mean global value by more than 50%. The greatest variability occurred in patients with acute subdural hematomas and diffuse (bihemispheric) injuries. This variability in CO 2 vasoresponsivity has important implications for the effective and safe management of intracranial hypertension that frequently accompanies severe head injury.(Neurosurgery 29: 869-873, 1991)
登录
查看更多内容
影响因子:
4.1
作者:
J. Overgaard;C. Mosdal;W. Tweed
通讯作者:
W. Tweed
影响因子:
2.1
作者:
G. Cold;F. Jensen;R. Malmros
通讯作者:
R. Malmros
影响因子:
4.1
作者:
NORDSTROM, CH;MESSETER, K;RYDING, E
通讯作者:
RYDING, E
影响因子:
2.4
作者:
M. Rossanda;L. Boselli;A. Casteli;C. Corona;F. Erminio;M. Nardini;M. Porta;C. Villa
通讯作者:
C. Villa
DOI:
10.1136/jnnp.50.12.1584
发表时间:
1987
期刊:
Journal of Neurology, Neurosurgery & Psychiatry
影响因子:
--
作者:
D. Fish;T. Lewis;D. Brooks;E. Zilkha;R. Wise;B. Kendall
通讯作者:
B. Kendall