Nontuberculous Mycobacteria in Noncystic Fibrosis Bronchiectasis.
Nontuberculous Mycobacteria in Noncystic Fibrosis Bronchiectasis.
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DOI：
10.1155/2015/197950
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发表时间：
2015
影响因子：
--
通讯作者：
Aliberti S
中科院分区：
文献类型：
--
作者：
Bonaiti G;Pesci A;Marruchella A;Lapadula G;Gori A;Aliberti S
在过去的几十年里，越来越多的人对非囊性纤维化支气管扩张症（NCFBE）患者的非结核分枝杆菌（NTM）进行了评估。本文就NTM与NCFBE的相关性，包括发病机制、影像学特征、诊断和治疗等方面进行综述。支气管扩张和NTM肺病是有联系的，但哪一个先来仍然是一个悬而未决的问题。NCFBE中NTM肺病的发生率在研究中从5%到30%不等。最常见的物种是MAC。受NTM感染影响的NCFBE患者经常出现合并感染，包括其他不同的NTM菌种和微生物，如铜绿假单胞菌。一旦诊断为NTM疾病，开始治疗并不总是强制性的。应考虑分离的NTM种属、患者的病情、疾病的严重程度及其演变。伴有NTM的NCFBE患者疾病进展的危险因素是低体重指数、空洞性疾病、实变和就诊时大环内酯类耐药。
During the past decades, a growing interest has been raised in evaluating nontuberculous mycobacteria (NTM) in patients with noncystic fibrosis bronchiectasis (NCFBE). This paper reviews several aspects of the correlations between NTM and NCFBE, including pathogenesis, radiological features, diagnosis, and management. Bronchiectasis and NTM lung disease are connected, but which one comes first is still an unresolved question. The rate of NTM lung disease in NCFBE varies through the studies, from 5% to 30%. The most frequent species isolated is MAC. NCFBE patients affected by NTM infection frequently present coinfections, including both other different NTM species and microorganisms, such as P. aeruginosa. Once a diagnosis of NTM disease has been reached, the initiation of therapy is not always mandatory. NTM species isolated, patients' conditions, and disease severity and its evolution should be considered. Risk factors for disease progression in NCFBE patients with NTM are low body mass index, cavitary disease, consolidations, and macrolide resistance at presentation.
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DOI：
10.2174/1874306401004010076
发表时间：
2010-08-08
期刊：
The open respiratory medicine journal
影响因子：
--
作者：
Khan, Zinobia;Miller, Albert;Donath, Joseph
通讯作者：
Donath, Joseph
影响因子：
5.8
作者：
Haverkamp, MH;van Dissel, JT;Holland, SM
通讯作者：
Holland, SM
DOI：
10.1164/ajrccm.161.4.9906094
发表时间：
2000-04-01
影响因子：
24.7
作者：
Kubo, K;Yamazaki, Y;Kamijou, Y
通讯作者：
Kamijou, Y
影响因子：
5.7
作者：
Griffith, David E.;Aksamit, Timothy R.
通讯作者：
Aksamit, Timothy R.
影响因子：
--
作者：
Chan, Edward D.;Kaminska, Aleksandra M.;Shapiro, Leland
通讯作者：
Shapiro, Leland