Predicting domain-domain interactions using a parsimony approach.
Predicting domain-domain interactions using a parsimony approach.
复制标题
使用简约方法预测域域相互作用。
DOI:
10.1186/gb-2006-7-11-r104
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发表时间:
2006
期刊:
影响因子:
12.3
通讯作者:
Przytycka TM
中科院分区:
文献类型:
--
作者:
Guimarães KS;Jothi R;Zotenko E;Przytycka TM
A new parsimony approach for the prediction of domain-domain interactions is presented and demonstrated to provide improvement in prediction coverage and accuracy. We propose a novel approach to predict domain-domain interactions from a protein-protein interaction network. In our method we apply a parsimony-driven explanation of the network, where the domain interactions are inferred using linear programming optimization, and false positives in the protein network are handled by a probabilistic construction. This method outperforms previous approaches by a considerable margin. The results indicate that the parsimony principle provides a correct approach for detecting domain-domain contacts.
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影响因子:
64.8
作者:
Gavin, AC;Bösche, M;Superti-Furga, G
通讯作者:
Superti-Furga, G
影响因子:
7
作者:
Deng, MH;Mehta, S;Chen, T
通讯作者:
Chen, T
影响因子:
3
作者:
Scheel H;Hofmann K
通讯作者:
Hofmann K
DOI:
10.1073/pnas.092147999
发表时间:
2002-04-30
影响因子:
11.1
作者:
Aloy, P;Russell, RB
通讯作者:
Russell, RB
影响因子:
56.9
作者:
Li, SM;Armstrong, CM;Vidal, M
通讯作者:
Vidal, M