Interactions between inflammation and female sexual desire and arousal function.

Interactions between inflammation and female sexual desire and arousal function.
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DOI:
10.1007/s11930-019-00218-7
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发表时间:
2019-12
影响因子:
2
通讯作者:
Lorenz TK
Lorenz TK
中科院分区:
其他
文献类型:
--
作者:
Lorenz TK

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描述炎症与女性性功能之间相互作用的研究现状。炎症可能通过直接(神经)和间接(内分泌,血管,社会/行为)途径干扰女性性欲和性唤起。炎症对性功能的影响存在显着的性别差异,这是由于生殖调节的进化选择压力不同。多种炎症相关疾病与女性性功能障碍的风险相关,包括心血管疾病、代谢综合征和慢性疼痛。临床意义包括需要对炎症相关疾病患者的性功能障碍进行常规评估,抗炎饮食改善性欲和唤醒功能的潜力,以及考虑慢性炎症作为激素治疗性效应的调节剂。尽管有证据表明炎症在女性性功能障碍的发展和维持中起作用,但这些关联的确切性质仍不清楚。
To describe the current state of research on interactions between inflammation and female sexual function. Inflammation may interfere with female sexual desire and arousal via direct (neural) and indirect (endocrine, vascular, social/behavioral) pathways. There are significant sex differences in the effect of inflammation on sexual function, arising from different evolutionary selection pressures on regulation of reproduction. A variety of inflammation-related conditions are associated with risk of female sexual dysfunction, including cardiovascular disease, metabolic syndrome, and chronic pain. Clinical implications include the need for routine assessment for sexual dysfunction in patients with inflammation-related conditions, the potential for anti-inflammatory diets to improve sexual desire and arousal function, and consideration of chronic inflammation as moderator of sexual effects of hormonal treatments. Although the evidence points to a role for inflammation in the development and maintenance of female sexual dysfunction, the precise nature of these associations remains unclear.
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