Feasibility, Methodology, and Interpretation of Broad-Scale Assessment of Cardiorespiratory Fitness in a Large Community-Based Sample.
Feasibility, Methodology, and Interpretation of Broad-Scale Assessment of Cardiorespiratory Fitness in a Large Community-Based Sample.
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DOI：
10.1016/j.amjcard.2021.07.020
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发表时间：
2021-10-15
影响因子：
2.8
通讯作者：
Lewis, Gregory D.
中科院分区：
文献类型：
--
作者：
Nayor, Matthew;Shah, Ravi, V;Tanguay, Melissa;Blodgett, Jasmine B.;Chernofsky, Ariel;Miller, Patricia E.;Xanthakis, Vanessa;Malhotra, Rajeev;Houstis, Nicholas E.;Velagaleti, Raghava S.;Larson, Martin G.;Vasan, Ramachandran S.;Lewis, Gregory D.
心肺适能（CRF）与健康状况有着复杂的关系。CRF量化的最佳方法是通过评估峰值摄氧量（VO2），但这种测量主要局限于小转诊人群。在这里，我们描述了在一个以社区为基础的大型样本中对峰值VO2的评估和意志努力的确定的协议和方法考虑。Framingham心脏研究的参与者在常规研究访问（2016-2019）中进行了最大增量斜坡周期几何心肺运动测试（CPET）。在进行多组分研究访问的3486名个体中，3116名（89%）完成了CPET。样本为中年人（54±9岁），女性占53%，体重指数28.3±5.6 kg/m2，高血压患者占48%，吸烟者占6%，糖尿病患者占8%。运动时间为12.0±2.1分钟（极限3.7-20.5）。无重大心血管事件发生。分别有98%、96%、90%、76%和57%的样本达到呼吸交换比（RER）峰值值≥1.0、≥1.05、≥1.10、≥1.15和≥1.20（平均RER峰值=1.22±0.10）。当RER峰值升高至≈1.10时，预测VO2峰值百分比、通气阈值VO2 / VO2峰值、心率反应和Borg（主观呼吸困难）评分发生急剧变化。与努力相关的CPET变量的变化更浅，达到更高的RER值。综上所述，在具有不同心血管风险特征的大样本中年社区居民中测量峰值VO2是可行且安全的。大多数中年人可达到峰值RER≥1.10，超过该阈值的RER不一定对应更高的峰值VO2值。
Cardiorespiratory fitness (CRF) is intricately related to health status. The optimal approach for CRF quantification is through assessment of peak oxygen uptake (VO2), but such measurements have been largely confined to small referral populations. Here we describe protocols and methodological considerations for peak VO2 assessment and determination of volitional effort in a large community-based sample. Maximum incremental ramp cycle ergometry cardiopulmonary exercise testing (CPET) was performed by Framingham Heart Study participants at a routine study visit (2016–2019). Of 3486 individuals presenting for a multi-component study visit, 3116 (89%) completed CPET. The sample was middle-aged (54±9 years), with 53% women, body mass index 28.3±5.6 kg/m2, 48% with hypertension, 6% smokers, and 8% with diabetes. Exercise duration was 12.0±2.1 minutes (limits 3.7–20.5). No major cardiovascular events occurred. A total of 98%, 96%, 90%, 76%, and 57% of the sample reached peak respiratory exchange ratio (RER) values of ≥1.0, ≥1.05, ≥1.10, ≥1.15, and ≥1.20, respectively (mean peak RER=1.22±0.10). With rising peak RER values up to ≈1.10, steep changes were observed for percent predicted peak VO2, VO2 at the ventilatory threshold/peak VO2, heart rate response, and Borg (subjective dyspnea) scores. More shallow changes for effort dependent CPET variables were observed with higher achieved RER values. In conclusion, measurement of peak VO2 is feasible and safe in a large sample of middle-aged, community-dwelling individuals with heterogeneous cardiovascular risk profiles. Peak RER ≥1.10 was achievable by the majority of middle-aged adults and RER values beyond this threshold did not necessarily correspond to higher peak VO2 values.
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影响因子：
4.8
作者：
Mezzani, A;Corrà, U;Giannuzzi, P
通讯作者：
Giannuzzi, P
影响因子：
9.7
作者：
Nayor, Matthew;Xanthakis, Vanessa;Lewis, Gregory D.
通讯作者：
Lewis, Gregory D.
DOI：
10.1249/mss.0000000000002344
发表时间：
2020-09-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Wagner, Jonathan;Niemeyer, Max;Knaier, Raphael
通讯作者：
Knaier, Raphael
DOI：
10.1249/00005768-198205000-00012
发表时间：
1982-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
BORG, GAV
通讯作者：
BORG, GAV
影响因子：
24
作者：
Clausen, Johan S. R.;Marott, Jacob L.;Jensen, Magnus T.
通讯作者：
Jensen, Magnus T.