Prevalence and associated factors of diabetic retinopathy in Beijing, China: a cross-sectional study.
Prevalence and associated factors of diabetic retinopathy in Beijing, China: a cross-sectional study.
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DOI：
10.1136/bmjopen-2016-015473
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发表时间：
2017-08-30
期刊：
影响因子：
2.9
通讯作者：
Yang JK
中科院分区：
文献类型：
--
作者：
Cui J;Ren JP;Chen DN;Xin Z;Yuan MX;Xu J;You QS;Yang JK
该研究旨在确定中国人群中糖尿病视网膜病变（DR）的确切危险因素，使用来自中国北京的17985名个体的队列。横断面研究。医院。17985人来自中国北京。这是一项横断面研究，研究对象为2010年7月至2011年3月和2014年3月至2015年2月在北京同仁医院进行常规健康检查期间招募的昌平地区（中国北京）常住居民。由经验丰富的眼科医生进行眼部检查。记录病史、身高、体重、体重指数（BMI）和血压。进行常规实验室检查。一般研究人群中DR的患病率为1.5%，糖尿病患者中为8.1%。与非DR组相比，糖尿病人群中DR组个体的病程更长，收缩压（SBP）、空腹血糖（FPG）和尿酸（UA）（男性）更高，而UA（女性）更低（均p<0.05）。多因素分析显示病程（p<0.001）、BMI（p=0.046）、SBP（p=0.012）、肌酐清除率（p=0.014）、UA（p=0.018）和FPG（p<0.001）是糖尿病患者DR的独立相关因素。糖尿病患者中DR的患病率为8.1%。病程、BMI、SBP、CCR、UA和FPG与DR独立相关。
The study aimed to determine the exact risk factors for diabetic retinopathy (DR) in the Chinese population using a cohort of 17 985 individuals from Beijing, China. Cross-sectional study. A hospital. 17 985 individuals from Beijing, China. This was a cross-sectional study of permanent residents from the Changping area (Beijing, China) recruited from July 2010 to March 2011 and from March 2014 to February 2015 during a routine health examination at the Tongren Hospital of Beijing. Eye examinations were conducted by experienced ophthalmologists. Medical history, height, weight, body mass index (BMI) and blood pressure were recorded. Routine laboratory examinations were performed. The prevalence of DR was 1.5% in the general study population and 8.1% among individuals with diabetes. Compared with the non-DR group, individuals in the DR group in the diabetes population had longer disease duration, higher systolic blood pressure (SBP), fasting plasma glucose (FPG) and uric acid (UA) (in men) and lower UA (in women) (all p<0.05). The multivariate analysis showed that disease duration (p<0.001), BMI (p=0.046), SBP (p=0.012), creatinine clearance rate (CCR) (p=0.014), UA (p=0.018) and FPG (p<0.001) were independently associated with DR in patients with diabetes. The prevalence of DR was 8.1% among patients with diabetes. Disease duration, BMI, SBP, CCR, UA and FPG were independently associated with DR.
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影响因子：
16.2
作者：
Raymond NT;Varadhan L;Reynold DR;Bush K;Sankaranarayanan S;Bellary S;Barnett AH;Kumar S;O'Hare JP;UK Asian Diabetes Study Retinopathy Study Group
通讯作者：
UK Asian Diabetes Study Retinopathy Study Group
影响因子：
3.7
作者：
Lim S;Kim KM;Kim MJ;Woo SJ;Choi SH;Park KS;Jang HC;Meigs JB;Wexler DJ
通讯作者：
Wexler DJ
影响因子：
3.8
作者：
Rooney, David;Lye, Weng Kit;Sabanayagam, Charumathi
通讯作者：
Sabanayagam, Charumathi
影响因子：
3.1
作者：
Gadkari SS;Maskati QB;Nayak BK
通讯作者：
Nayak BK
影响因子：
1.7
作者：
Xie, X. W.;Xu, L.;Wang, Y. X.
通讯作者：
Wang, Y. X.