Peripheral arterial elasticity changes derived by volume-oscillometry in reaction to hyperemia as a possible assessment of flow-mediated vasodilatation.
Peripheral arterial elasticity changes derived by volume-oscillometry in reaction to hyperemia as a possible assessment of flow-mediated vasodilatation.
复制标题
外周动脉弹性的变化是通过体积 - 尺度计量法对充血反应的反应，作为流动介导的血管舒张的可能评估。
DOI：
10.1038/s41598-022-22050-1
复制
发表时间：
2022-11-14
影响因子：
4.6
通讯作者：
中科院分区：
文献类型：
--
作者：
血流介导扩张（FMD）试验是常用的，也是评估血管内皮细胞功能的唯一技术。在这个测试中，反应性充血后的肱动脉直径的增加是由熟练的操作员使用超声精确测量的。这是一项仅限医院的检查，如果在家里方便地进行，会更有用。本文描述了研究外周动脉弹性变化影响的第一种方法，并展望了可能评估功能反应性的方法。最近开发的一种基于智能手机的仪器被用来测量手指和桡动脉的弹性特性，与刚度和血管舒张有关，作为由光容积振荡法得出的扩张压力的函数。成功获得15名正常志愿者上臂袖带闭合5分钟前后双动脉弹性变化。僵硬度指数值和血管舒张度指数值分别有显著降低和显著升高（p < 0.01），清楚地显示充血时预期的弹性变化，这与FMD试验的临床反应一致。结果表明，该方法可以方便地提供血管弹性和血管舒张的重要信息。作为一种方便的评估方法，它有望有助于动脉硬化性心血管筛查。
The flow-mediated dilation (FMD) test is commonly utilized and is the only technique for the assessment of vascular endothelial cell function. With this test, the augmentation of a brachial artery diameter following reactive hyperemia is measured precisely using ultrasonography by a skilled operator. This is a hospital-only test, and would be more useful if conveniently performed at home. This paper describes a first approach for studying the impact of changes in peripheral arterial elasticity, with prospects towards possible assessment of functional reactivity. A recently developed smartphone-based instrument was used to measure elastic properties of finger and radial arteries, related to stiffness and vasodilatation, as a function of distending pressure derived by photo-plethysmographic volume-oscillometry. Elasticity changes in both arteries before and after a 5-min supra-systolic upper-arm cuff occlusion were successfully obtained in 15 normal volunteers. The index-values of stiffness and vasodilatation showed, respectively, a significant decrease and increase (p < 0.01), demonstrating clearly the expected elasticity changes with hyperemia, which could be consistent with the clinically-stated reaction in an FMD test. The results suggest that this method could easily provide important information of both elasticity and vasodilatation. It appears promising as a convenient assessment method to contribute to arteriosclerotic cardiovascular screening.
登录
查看更多内容
颈动脉多普勒超声检查的一般原理。
DOI：
10.14366/usg.13018
发表时间：
2014-01
期刊：
Ultrasonography (Seoul, Korea)
影响因子：
--
作者：
Lee W
通讯作者：
Lee W
DOI：
10.1161/circoutcomes.118.005375
发表时间：
2019-06-01
影响因子：
6.9
作者：
Nowbar, Alexandra N.;Gitto, Mauro;Al-Lamee, Rasha
通讯作者：
Al-Lamee, Rasha
影响因子：
1.2
作者：
Rodriguez-Miguelez, Paula;Seigler, Nichole;Harris, Ryan A.
通讯作者：
Harris, Ryan A.
影响因子：
8.3
作者：
Harris, Ryan A.;Nishiyama, Steven K.;Richardson, Russell S.
通讯作者：
Richardson, Russell S.
影响因子：
2.5
作者：
Wu, Fu-Lien;Zheng, Zhi;Jan, Yih-Kuen
通讯作者：
Jan, Yih-Kuen