The role of aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use: results of a pooled-analysis from seven European countries.
The role of aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use: results of a pooled-analysis from seven European countries.
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飞机噪音烦扰和噪音敏感性在飞机噪音水平和药物使用之间的关系中的作用：来自七个欧洲国家的汇总分析结果。
DOI：
10.1186/s12889-021-10280-3
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发表时间：
2021-02-05
影响因子：
4.5
通讯作者：
Evrard AS
中科院分区：
文献类型：
--
作者：
Baudin C;Lefèvre M;Babisch W;Cadum E;Champelovier P;Dimakopoulou K;Houthuijs D;Lambert J;Laumon B;Pershagen G;Stansfeld S;Velonaki V;Hansell AL;Evrard AS
很少有研究在分析飞机噪音对健康的影响时考虑飞机噪音的烦扰和噪声敏感性，特别是与药物使用有关的影响。这项研究旨在调查这两个因素在飞机噪音水平和药物使用之间的关系中的调节和中介作用，这些居民来自10个欧洲机场，包括鬣狗和Debats的研究。通过在家中进行面对面的访谈，收集了有关飞机噪音烦扰、噪音敏感性、药物使用以及人口统计、社会经济和生活方式因素的信息。根据解剖治疗化学药物(ATC)分类对药物进行编码。通过使用地理信息系统(GIS)方法将参与者的家庭地址与噪声等值线联系起来，估计室外飞机噪声暴露。使用了调整了潜在混杂因素的Logistic回归。此外，巴伦和肯尼的建议被用来调查飞机噪音烦扰和噪音敏感性的调节和调节作用。只有在英国，夜间飞机噪音水平与降压药物显著相关(OR = 为1.43，95%CI为1.19~1.73，夜间噪音增加10 分贝(A))。没有发现与其他药物有关。飞机噪音骚扰与使用抗高血压药物(OR = 1.33，95%CI 1.14~1.56)、抗焦虑药物(OR = 1.48，95%CI 1.08~2.05)、催眠药和镇静剂(OR = 1.60，95%CI 1.07~2.39)和抗哮喘药物(OR = 1.44，95%CI 1.07~1.96)显著相关，不同国家之间无差异。噪声敏感性与几乎所有药物显著相关，除了使用抗哮喘药物外，显示出随着噪声敏感性水平的增加，OR增加，只有使用抗高血压药物的国家之间的OR存在差异。研究结果还表明，飞机噪声烦扰在飞机噪声水平与药物使用之间的关系中起中介作用，飞机噪声烦扰和噪声敏感度在飞机噪声水平与药物使用之间的关系中起调节作用。本研究结果与迄今已有的少数研究结果相一致，这些研究表明，在分析暴露于飞机噪音对健康的影响时，应同时考虑飞机噪音烦扰和噪音敏感性。网上版载有补充材料，可在10.1186/s12889-021-10280-3查阅。
Few studies have considered aircraft noise annoyance and noise sensitivity in analyses of the health effects of aircraft noise, especially in relation to medication use. This study aims to investigate the moderating and mediating role of these two factors in the relationship between aircraft noise levels and medication use among 5860 residents of ten European airports included in the HYENA and DEBATS studies. Information on aircraft noise annoyance, noise sensitivity, medication use, and demographic, socio-economic and lifestyle factors was collected during a face-to-face interview at home. Medication was coded according to the Anatomical Therapeutic Chemical (ATC) classification. Outdoor aircraft noise exposure was estimated by linking the participant’s home address to noise contours using Geographical Information Systems (GIS) methods. Logistic regressions with adjustment for potential confounding factors were used. In addition, Baron and Kenny’s recommendations were followed to investigate the moderating and mediating effects of aircraft noise annoyance and noise sensitivity. A significant association was found between aircraft noise levels at night and antihypertensive medication only in the UK (OR = 1.43, 95%CI 1.19–1.73 for a 10 dB(A)-increase in Lnight). No association was found with other medications. Aircraft noise annoyance was significantly associated with the use of antihypertensive medication (OR = 1.33, 95%CI 1.14–1.56), anxiolytics (OR = 1.48, 95%CI 1.08–2.05), hypnotics and sedatives (OR = 1.60, 95%CI 1.07–2.39), and antasthmatics (OR = 1.44, 95%CI 1.07–1.96), with no difference between countries. Noise sensitivity was significantly associated with almost all medications, with the exception of the use of antasthmatics, showing an increase in ORs with the level of noise sensitivity, with differences in ORs among countries only for the use of antihypertensive medication. The results also suggested a mediating role of aircraft noise annoyance and a modifying role of both aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use. The present study is consistent with the results of the small number of studies available to date suggesting that both aircraft noise annoyance and noise sensitivity should be taken into account in analyses of the health effects of exposure to aircraft noise. The online version contains supplementary material available at 10.1186/s12889-021-10280-3.
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影响因子：
7.6
作者：
BARON, RM;KENNY, DA
通讯作者：
KENNY, DA
影响因子：
4.7
作者：
Fields, JM;De Jong, RG;Schumer, R
通讯作者：
Schumer, R
影响因子：
9.8
作者：
Babisch, Wolfgang;Pershagen, Goran;Hansell, Anna L.
通讯作者：
Hansell, Anna L.
影响因子：
5.4
作者：
Eriksson, Charlotta;Rosenlund, Mats;Bluhm, Gosta
通讯作者：
Bluhm, Gosta
影响因子：
11.8
作者：
Eze, Ikenna C.;Foraster, Maria;Probst-Hensch, Nicole
通讯作者：
Probst-Hensch, Nicole