Health behaviors and cancer screening practices in long-term survivors of hematopoietic cell transplantation (HCT): a report from the BMT Survivor Study.
Health behaviors and cancer screening practices in long-term survivors of hematopoietic cell transplantation (HCT): a report from the BMT Survivor Study.
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DOI：
10.1038/bmt.2011.60
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发表时间：
2012-02
影响因子：
4.8
通讯作者：
Bhatia S
中科院分区：
文献类型：
--
作者：
Armenian SH;Sun CL;Francisco L;Baker KS;Weisdorf DJ;Forman SJ;Bhatia S
接受HCT的患者患慢性疾病的风险增加，包括第二恶性肿瘤和心血管疾病。人们对HCT幸存者的健康行为和癌症筛查做法是否能降低这些疾病的风险知之甚少。BMTSS检查了1976年至1998年间接受HCT的个体的健康行为和癌症筛查实践，并存活了2年以上。如果一个人目前是吸烟者，并且在饮酒的日子里报告有危险的酒精摄入量（≥4杯/天[男性]，≥3杯/天[女性]），那么他的健康行为被认为是高风险的。癌症筛查评估按照美国癌症协会的建议进行。1040名幸存者：42.7%接受了同种异体HCT；女性占43.8%；HCT的中位时间：7.4年（范围2.0-27.7年）。参与研究时的中位年龄：43.8岁（范围18.3-73.0岁）。多因素回归分析显示，参与研究时年龄较小（<35岁）（比值比[OR]=4.7, p<0.01）和教育程度较低（<大学学历：OR=2.1, p<0.01）与高危行为显著相关。与性别匹配的兄弟姐妹对照组（N=309）相比，幸存者报告高危行为的可能性显著降低（OR=0.5; p<0.01），更有可能进行乳房x光筛查（OR=2.8; p=0.05）。
Patients undergoing HCT are at increased risk of chronic health conditions, including second malignant neoplasms and cardiovascular disease. Little is known about health behaviors and cancer screening practices among HCT survivors that could moderate the risk of these conditions. The BMTSS examined health behaviors and cancer screening practices in individuals who underwent HCT between 1976 and 1998, and survived 2+ years. Health behavior was deemed high-risk if an individual was a current smoker and if they reported risky alcohol intake (≥4 drinks/day [males], ≥ 3 drinks/day [females]) on days of alcohol consumption. Cancer screening assessment was per American Cancer Society recommendations. There were 1040 survivors: 42.7% underwent allogeneic HCT; 43.8% were female; median time from HCT: 7.4 years (range 2.0–27.7 years). Median age at study participation: 43.8 years (range 18.3–73.0 years). Multivariate regression analysis revealed younger age (<35 years) at study participation (Odds Ratio [OR]=4.7; p<0.01) and lower education (<college: OR=2.1; p<0.01) to be significantly associated with high-risk behavior. Survivors were significantly less likely to report high-risk behavior (OR=0.5; p<0.01), and more likely to have had a screening mammogram (OR=2.8; p=0.05) when compared to gender-matched sibling controls (N=309).
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影响因子：
4.8
作者：
Ranke, MB;Schwarze, CP;Niethammer, D
通讯作者：
Niethammer, D
影响因子：
4.3
作者：
Marks, David I.;Ballen, Karen;Rizzo, J. Douglas
通讯作者：
Rizzo, J. Douglas
DOI：
10.1007/s11764-007-0007-0
发表时间：
2007-03-01
期刊：
Journal of cancer survivorship : research and practice
影响因子：
--
作者：
Mayer, Deborah K;Terrin, Norma C;Mooney, Kathleen H
通讯作者：
Mooney, Kathleen H
影响因子：
4.8
作者：
Louie, AD;Robison, LL;Bhatia, S
通讯作者：
Bhatia, S
影响因子：
45.3
作者：
Blanchard, Christopher M.;Courneya, Kerry S.;Stein, Kevin
通讯作者：
Stein, Kevin