Lifetime physical activity and pelvic organ prolapse in middle-aged women.

Lifetime physical activity and pelvic organ prolapse in middle-aged women.
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DOI:
10.1016/j.ajog.2014.01.035
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发表时间:
2014-05
影响因子:
9.8
通讯作者:
Egger, Marlene J.
Egger, Marlene J.
中科院分区:
医学1区
文献类型:
--
作者:
Nygaard, Ingrid E.;Shaw, Janet M.;Bardsley, Tyler;Egger, Marlene J.

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在病例对照研究中,确定盆腔器官脱垂(POP)是否与总体终身体力活动(结合休闲、户外、家庭、职业)以及终身休闲、终身剧烈和青少年剧烈活动相关。主要从初级保健诊所招募了191例POP病例(定义为最大阴道下降≥处女膜以下1 cm)和191例年龄和招募部位匹配的对照(定义为最大阴道下降≤处女膜以上1 cm),年龄在39-65岁之间,无或轻度尿失禁。参与者完成了终身体力活动(LPAQ)和职业(OQ)问卷,回顾了4个年龄段的活动。我们对身体活动测量进行了单独的逻辑回归模型。与对照组相比,POP病例的BMI和产次更大。中位总体终生活动,以MET小时/周表示,病例组和对照组之间无显著差异。在调整分析中,我们观察到POP的几率与总体终身体力活动,终身休闲活动或终身剧烈活动之间没有关联。青少年剧烈活动与POP之间存在轻微显著的非线性关系,报告剧烈活动≥ 21小时/周的女性POP的对数比值增加(p=0.046)。终身体力活动不会增加中年妇女不寻求POP. Strengthened活动在青少年时期可能会赋予更高的POP. This关系和潜在的作用,体力活动和POP发病率的解剖POP的几率应进行前瞻性评估。
To determine, in a case-control study, whether pelvic organ prolapse (POP) is associated with overall lifetime physical activity (combined leisure, outdoor, household, occupational), and lifetime leisure, lifetime strenuous, and teen years strenuous activity. 191 POP cases (defined as maximal vaginal descent ≥1 cm below the hymen) and 191 age and recruitment-site matched controls (defined as maximal vaginal descent ≤1 cm above the hymen) between 39–65 years with no or mild urinary incontinence, were recruited chiefly from primary care clinics. Participants completed Lifetime Physical Activity (LPAQ) and Occupation (OQ) Questionnaires, recalling activities during 4 age epochs. We performed separate logistic regression models for physical activity measures. Compared to controls, POP cases had greater BMI and parity. Median overall lifetime activity, expressed in MET-hours/week, did not differ significantly between cases and controls. In adjusted analyses, we observed no associations between odds of POP and overall lifetime physical activity, lifetime leisure activity, or lifetime strenuous activity. There was a marginally significant nonlinear relationship between teen strenuous activity and POP with an increase in the log-odds of POP for women reporting ≥ 21 hours/week of strenuous activity (p=0.046). Lifetime physical activity does not increase the odds of anatomic POP in middle-aged women not seeking care for POP. Strenuous activity during teenage years may confer higher odds of POP. This relationship and the potential role of physical activity and POP incidence should be evaluated prospectively.
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