Assembly of the reovirus genome.
Assembly of the reovirus genome.
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呼肠孤病毒基因组的组装。
DOI：
10.1007/978-3-642-72092-5_3
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发表时间：
1998
影响因子：
--
通讯作者：
Joklik,WK
中科院分区：
文献类型：
--
作者：
Joklik,WK
During the early days of molecular virology, the presumed monomolecular nature of their genomes was considered to be one of the primary virtues of viruses. However, in 1969, irrefutable evidence surfaced that reovirus genomes consist not of one, but of ten molecules of double-stranded (ds)RNA (Shatkinet al. 1968). Further, it quickly became apparent that this was not a case of a “headful” mechanism at work, such as appears to operate for influenza virus, where virus particles probably contain random 11-segment collections of the eight actual influenza genome segment species, so that roughly one in 25 virus particles contains at least one of each and is therefore infectious (LambandChoppin1983;Enamiet al. 1991). By contrast, the assembly of genome segments to form the reovirus genome is an extraordinarily efficient and precise process because the ratio of virus particles to infectious units in carefully handled reovirus preparations is essentially 1 (1.6 or less) (Spendloveet al. 1970;Larsonet al. 1994).
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呼肠孤病毒RNA具有传染性。
影响因子：
3.7
作者：
Roner,MR;Sutphin,LA;Joklik,WK
通讯作者：
Joklik,WK
影响因子：
3.7
作者：
Jon R. Wiener;W. Joklik
通讯作者：
Jon R. Wiener;W. Joklik
呼肠孤病毒双温度敏感突变体的构建和表征。
DOI：
10.1073/pnas.94.13.6826
发表时间：
1997
影响因子：
11.1
作者：
Roner,MR;Nepliouev,I;Sherry,B;Joklik,WK
通讯作者：
Joklik,WK
呼肠孤病毒毒力的分子基础：S1 基因的作用。
DOI：
10.1073/pnas.74.12.5744
发表时间：
1977
影响因子：
11.1
作者：
H. Weiner;D. Drayna;D. Averill;B. Fields
通讯作者：
B. Fields
呼肠孤病毒温度敏感突变体和缺失突变体之间的互补
影响因子：
5.4
作者：
D. Spandidos;A. F. Graham
通讯作者：
A. F. Graham