Carnitine metabolism in chronic liver disease.

Carnitine metabolism in chronic liver disease.
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慢性肝病中的肉碱代谢。

DOI:
10.1016/0024-3205(96)00343-8
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发表时间:
1996
期刊:
影响因子:
6.1
通讯作者:
Stephan Krähenbühl
Stephan Krähenbühl
中科院分区:
医学2区
文献类型:
--
作者:
Stephan Krähenbühl

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肝脏是肉碱代谢和肉碱向体内分布的中心器官。因此,患有某些类型慢性肝病的患者和实验动物肉碱代谢受损也就不足为奇了。在这篇综述中,讨论了与慢性肝病相关的肉碱代谢变化以及肉碱作为治疗剂在其中一些疾病中的作用。
The liver is a central organ for carnitine metabolism and for the distribution of carnitine to the body. It is therefore not surprising that carnitine metabolism is impaired in patients and experimental animals with certain types of chronic liver disease. In this review, the changes in carnitine metabolism associated with chronic liver disease and the role of carnitine as a therapeutic agent in some of these conditions are discussed.
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