Chinese Medicinal Herbs Targeting the Gut-Liver Axis and Adipose Tissue-Liver Axis for Non-Alcoholic Fatty Liver Disease Treatments: The Ancient Wisdom and Modern Science.
Chinese Medicinal Herbs Targeting the Gut-Liver Axis and Adipose Tissue-Liver Axis for Non-Alcoholic Fatty Liver Disease Treatments: The Ancient Wisdom and Modern Science.
复制标题
针对肠道-肝轴和脂肪组织-肝轴的中药治疗非酒精性脂肪肝：古代智慧与现代科学
DOI：
10.3389/fendo.2020.572729
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发表时间：
2020
影响因子：
5.2
通讯作者：
Su T
中科院分区：
文献类型：
--
作者：
Zhang S;Wong YT;Tang KY;Kwan HY;Su T
非酒精性脂肪性肝病（NAFLD）是全球最常见的慢性肝病之一。NAFLD的发病机制复杂。一线西药只能改善NAFLD的症状。相反，中医药在解释NAFLD方面的独特性和整体治疗方法导致了有希望的治疗效果。近年来的研究表明，肠-肝轴和脂肪组织-肝轴在NAFLD的发生发展中起重要作用。有趣的是，随着先进的技术，许多草药配方被发现以肠道-肝脏轴和脂肪组织-肝脏轴为目标，并解决NAFLD中的炎症。这是第一篇综述，总结了目前在NAFLD治疗中针对两个轴的中药配方的研究结果。这篇综述不仅展示了现代药理学研究如何诠释中医的古老智慧，而且为NAFLD的中医药治疗的进一步发展提供了有价值的信息。
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. The pathogenesis of NAFLD is complex. Frontline western medicines only ameliorate the symptoms of NAFLD. On the contrary, the uniqueness of Chinese medicine in its interpretation of NAFLD and the holistic therapeutic approach lead to a promising therapeutic efficacy. Recent studies reveal that the gut–liver axis and adipose tissue–liver axis play important roles in the development of NAFLD. Interestingly, with advanced technology, many herbal formulae are found to target the gut–liver axis and adipose tissue–liver axis and resolve the inflammation in NAFLD. This is the first review summarizes the current findings on the Chinese herbal formulae that target the two axes in NAFLD treatment. This review not only demonstrates how the ancient wisdom of Chinese medicine is being interpreted by modern pharmacological studies, but also provides valuable information for the further development of the herbal-based treatment for NAFLD.
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影响因子：
1.9
作者：
Abenavoli, Ludovico;Peta, Valentina
通讯作者：
Peta, Valentina
影响因子：
5.6
作者：
Cui, Yizhe;Chang, Renxu;Xu, Chuang
通讯作者：
Xu, Chuang
影响因子：
13.5
作者：
Bechmann, Lars P.;Kocabayoglu, Peri;Canbay, Ali
通讯作者：
Canbay, Ali
DOI：
10.1177/2042018815574229
发表时间：
2015-04-01
影响因子：
3.8
作者：
Aghamohammadzadeh, Nasser;Niafar, Mitra;Ahadi, Hamidreza
通讯作者：
Ahadi, Hamidreza
影响因子：
3.1
作者：
Czaja MJ
通讯作者：
Czaja MJ