Afferent nerves regulating the cough reflex: mechanisms and mediators of cough in disease.
Afferent nerves regulating the cough reflex: mechanisms and mediators of cough in disease.
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DOI：
10.1016/j.otc.2009.11.012
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发表时间：
2010-02
影响因子：
1.7
通讯作者：
Canning, Brendan J.
中科院分区：
文献类型：
--
作者：
Canning, Brendan J.
Bronchopulmonary C-fibers and acid-sensitive, capsaicin-insensitive mechanoreceptors innervating the larynx, trachea and large bronchi regulate the cough reflex. These vagal afferent nerves may interact centrally with sensory input arising from afferent nerves innervating the intrapulmonary airways or even extrapulmonary afferents such as those innervating the nasal mucosa and esophagus to produce chronic cough or enhanced cough responsiveness. The mechanisms of cough initiation in health and in disease are briefly described.
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