Society for Reproductive Biology Founders' Lecture 2006 - life in the pouch: womb with a view.

Society for Reproductive Biology Founders' Lecture 2006 - life in the pouch: womb with a view.
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2006 年生殖生物学学会创始人演讲 - 育儿袋中的生活:有风景的子宫。

DOI:
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发表时间:
2006
期刊:
Reproduction, Fertility and Development
影响因子:
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通讯作者:
M. Renfree
M. Renfree
中科院分区:
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文献类型:
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作者:
M. Renfree

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有袋动物在相对较短的妊娠期后产下未发育成熟的幼崽,但有一个漫长而复杂的哺乳期,幼崽通常在育儿袋中发育。它们的胎生繁殖方式是用胎盘代替哺乳,用脐带代替乳头。有袋动物进化出的特殊适应性为我们了解所有哺乳动物的生殖进化提供了独特的视角。有袋动物保持着许多哺乳动物的生殖“记录”,例如,它们有已知最短的妊娠期,但最长的胚胎滞育,最小的新生儿,但最长的精子。它们有助于我们了解许多哺乳动物的生殖事件,包括胚胎滞育和发育、出生行为、性别决定、性别分化、哺乳和季节性繁殖。由于有袋动物在遗传上已经从真兽哺乳动物中分离出来超过1.25亿年,两个有袋动物物种的基因组测序使比较基因组生物学成为一个令人兴奋和重要的新研究领域。这篇综述将展示对有袋动物的研究如何拓宽了我们对哺乳动物繁殖和发育的理解,强调一些非常基本的机制,这些机制是今天所有有袋动物和真兽哺乳动物所共有的。
Marsupials give birth to an undeveloped altricial young after a relatively short gestation period, but have a long and sophisticated lactation with the young usually developing in a pouch. Their viviparous mode of reproduction trades placentation for lactation, exchanging the umbilical cord for the teat. The special adaptations that marsupials have developed provide us with unique insights into the evolution of all mammalian reproduction. Marsupials hold many mammalian reproductive 'records', for example they have the shortest known gestation but the longest embryonic diapause, the smallest neonate but the longest sperm. They have contributed to our knowledge of many mammalian reproductive events including embryonic diapause and development, birth behaviour, sex determination, sexual differentiation, lactation and seasonal breeding. Because marsupials have been genetically isolated from eutherian mammals for over 125 million years, sequencing of the genome of two marsupial species has made comparative genomic biology an exciting and important new area of investigation. This review will show how the study of marsupials has widened our understanding of mammalian reproduction and development, highlighting some mechanisms that are so fundamental that they are shared by all today's marsupial and eutherian mammals.
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发表时间: 2004-07-13
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DOI: 10.1095/biolreprod47.4.644
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